Version 5.4
Mus musculus Gene: Vps54
Summary
InnateDB Gene IDBG-153182.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Vps54
Gene Name vacuolar protein sorting 54 (yeast)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000020128
Encoded Proteins
IDBP-153184
vacuolar protein sorting 54 (yeast)
IDBP-262095
vacuolar protein sorting 54 (yeast)
IDBP-534179
vacuolar protein sorting 54 (yeast)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143952:
This gene encodes for a protein that in yeast forms part of a trimeric vacuolar-protein-sorting complex that is required for retrograde transport of proteins from prevacuoles to the late Golgi compartment. As in yeast, mammalian Vps54 proteins contain a coiled-coil region and dileucine motifs. Alternative splicing results in multiple transcript variants encoding different isoforms [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:21239281-21321136
Strand Forward strand
Band A3.1
Transcripts
ENSMUST00000006221 ENSMUSP00000006221
ENSMUST00000109578 ENSMUSP00000105206
ENSMUST00000132017 ENSMUSP00000116739
ENSMUST00000132146
ENSMUST00000143932
ENSMUST00000153411
ENSMUST00000153159
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0015031 protein transport
GO:0040007 growth
GO:0042147 retrograde transport, endosome to Golgi
GO:0048873 homeostasis of number of cells within a tissue
GO:0050881 musculoskeletal movement
GO:0060052 neurofilament cytoskeleton organization
Cellular Component
GO:0000938 GARP complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000143952
View Gene Order
ENSBTAG00000000115
Not yet available
Cross-References
SwissProt Q5SPW0
TrEMBL Q3UVJ8
UniProt Splice Variant
Entrez Gene 245944
UniGene Mm.170103 Mm.404035
RefSeq NM_139061 XM_006514697 XM_006514699 NM_001290628 XM_006514698
OMIM
CCDS CCDS24463 CCDS70147
HPRD
IMGT
MGI ID MGI:2178798
MGI Symbol Vps54
EMBL AB052761 AK077306 AK137211 AL669979 AL833772 BC023474 BC024789 BC025012
GenPept AAH23474 AAH24789 AAH25012 BAC36741 BAC53794 BAE23271 CAI24173 CAI24174 CAI26092 CAI26093
RNA Seq Atlas 245944

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca