Version 5.4
Homo sapiens Gene: PLA2G10
Summary
InnateDB Gene IDBG-15446.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PLA2G10
Gene Name phospholipase A2, group X
Synonyms GXPLA2; GXSPLA2; SPLA2
Species Homo sapiens
Ensembl Gene ENSG00000069764
Encoded Proteins
IDBP-369121
phospholipase A2, group X
IDBP-753751
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 16:14672545-14694669
Strand Reverse strand
Band p13.12
Transcripts
ENST00000438167 ENSP00000393847
ENST00000567462 ENSP00000456433
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004620 phospholipase activity
GO:0004623 phospholipase A2 activity
GO:0005509 calcium ion binding
Biological Process
GO:0006644 phospholipid metabolic process
GO:0006654 phosphatidic acid biosynthetic process
GO:0007411 axon guidance
GO:0010744 positive regulation of macrophage derived foam cell differentiation
GO:0010884 positive regulation of lipid storage
GO:0016042 lipid catabolic process
GO:0019369 arachidonic acid metabolic process
GO:0032270 positive regulation of cellular protein metabolic process
GO:0032308 positive regulation of prostaglandin secretion
GO:0036148 phosphatidylglycerol acyl-chain remodeling
GO:0036149 phosphatidylinositol acyl-chain remodeling
GO:0036150 phosphatidylserine acyl-chain remodeling
GO:0036151 phosphatidylcholine acyl-chain remodeling
GO:0036152 phosphatidylethanolamine acyl-chain remodeling
GO:0042632 cholesterol homeostasis
GO:0043030 regulation of macrophage activation
GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity
GO:0044281 small molecule metabolic process
GO:0046474 glycerophospholipid biosynthetic process
GO:0051977 lysophospholipid transport
GO:0090238 positive regulation of arachidonic acid secretion
GO:0090370 negative regulation of cholesterol efflux
Cellular Component
GO:0005576 extracellular region
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000022683
View Gene Order
Pathways
NETPATH
REACTOME
REACT_120829
Acyl chain remodelling of PC pathway
REACT_120722
Acyl chain remodelling of PI pathway
REACT_121384
Acyl chain remodelling of PS pathway
REACT_120906
Synthesis of PA pathway
REACT_121324
Acyl chain remodelling of PG pathway
REACT_121369
Acyl chain remodelling of PE pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_121401
Glycerophospholipid biosynthesis pathway
REACT_120870
Phospholipid metabolism pathway
REACT_111217
Metabolism pathway
KEGG
hsa00592
alpha-Linolenic acid metabolism pathway
hsa00590
Arachidonic acid metabolism pathway
hsa00564
Glycerophospholipid metabolism pathway
hsa00591
Linoleic acid metabolism pathway
hsa00565
Ether lipid metabolism pathway
hsa04270
Vascular smooth muscle contraction pathway
hsa04975
Fat digestion and absorption pathway
hsa04972
Pancreatic secretion pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.567366
RefSeq NM_003561 XM_006720958 XM_006725214
HUGO
OMIM
CCDS CCDS10555
HPRD 04674
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca