Mus musculus Gene: Grik4 | |||||||||||||||||||||||
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Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-154653.6 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | Grik4 | ||||||||||||||||||||||
Gene Name | glutamate receptor, ionotropic, kainate 4 | ||||||||||||||||||||||
Synonyms | 6330551K01Rik; GluK4; GluRgamma1; KA-1; KA1 | ||||||||||||||||||||||
Species | Mus musculus | ||||||||||||||||||||||
Ensembl Gene | ENSMUSG00000032017 | ||||||||||||||||||||||
Encoded Proteins |
glutamate receptor, ionotropic, kainate 4
glutamate receptor, ionotropic, kainate 4
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Protein Structure | |||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000149403:
This gene encodes a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory neurotransmitter in the central nervous system through activation of ligand-gated ion channels and G protein-coupled membrane receptors. The protein encoded by this gene forms functional heteromeric kainate-preferring ionic channels with the subunits encoded by related gene family members. [provided by RefSeq, Jul 2008] This gene encodes a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory neurotransmitter in the central nervous system through activation of ligand-gated ion channels and G protein-coupled membrane receptors. The protein encoded by this gene forms functional heteromeric kainate-preferring ionic channels with the subunits encoded by related gene family members. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013] |
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Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome 9:42518135-42944493 | ||||||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||||||
Band | A5.1 | ||||||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||
Species
Homo sapiens
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Gene ID
Gene Order
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Pathways | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME |
Ionotropic activity of Kainate Receptors pathway
Activation of Kainate Receptors upon glutamate binding pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
Activation of Ca-permeable Kainate Receptor pathway
Neuronal System pathway
Transmission across Chemical Synapses pathway
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KEGG |
Neuroactive ligand-receptor interaction pathway
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INOH | |||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME |
Neuronal System pathway
Ionotropic activity of Kainate Receptors pathway
Activation of Kainate Receptors upon glutamate binding pathway
Transmission across Chemical Synapses pathway
Activation of Ca-permeable Kainate Receptor pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
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KEGG |
Neuroactive ligand-receptor interaction pathway
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INOH | |||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||
Cross-References | |||||||||||||||||||||||
SwissProt | Q8BMF5 | ||||||||||||||||||||||
TrEMBL | |||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | 110637 | ||||||||||||||||||||||
UniGene | Mm.367909 Mm.370291 | ||||||||||||||||||||||
RefSeq | NM_175481 XM_006509943 XM_006509941 | ||||||||||||||||||||||
OMIM | |||||||||||||||||||||||
CCDS | CCDS23089 | ||||||||||||||||||||||
HPRD | |||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
MGI ID | MGI:95817 | ||||||||||||||||||||||
MGI Symbol | Grik4 | ||||||||||||||||||||||
EMBL | AC122449 AC136903 AC140387 AC160123 AK032029 | ||||||||||||||||||||||
GenPept | BAC27660 | ||||||||||||||||||||||
RNA Seq Atlas | 110637 | ||||||||||||||||||||||