Version 5.4
Mus musculus Gene: Spcs3
Summary
InnateDB Gene IDBG-155300.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Spcs3
Gene Name signal peptidase complex subunit 3 homolog (S. cerevisiae)
Synonyms 1810011E08Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000054408
Encoded Proteins
IDBP-717834
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000129128:
Gene Information
Type Protein coding
Genomic Location Chromosome 8:54520433-54529998
Strand Reverse strand
Band B1.3
Transcripts
ENSMUST00000067476 ENSMUSP00000136527
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0008233 peptidase activity
Biological Process
GO:0006465 signal peptide processing
GO:0006508 proteolysis
GO:0008150 biological_process
Cellular Component
GO:0005787 signal peptidase complex
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000129128
View Gene Order
ENSBTAG00000014146
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu03060
Protein export pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_19189
Synthesis, secretion, and deacylation of Ghrelin pathway
REACT_23824
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) pathway
REACT_24019
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) pathway
REACT_115902
SRP-dependent cotranslational protein targeting to membrane pathway
REACT_1014
Translation pathway
REACT_23974
Incretin synthesis, secretion, and inactivation pathway
REACT_17015
Metabolism of proteins pathway
REACT_160078
Peptide hormone metabolism pathway
REACT_71
Gene Expression pathway
KEGG
hsa03060
Protein export pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL Q6ZWQ7
UniProt Splice Variant
Entrez Gene 76687
UniGene Mm.86437
RefSeq NM_029701
OMIM
CCDS CCDS57621
HPRD
IMGT
MGI ID MGI:1923937
MGI Symbol Spcs3
EMBL AC102933 AK007432 AK048051 BC054817
GenPept AAH54817 BAB25035 BAC33224
RNA Seq Atlas 76687

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca