Version 5.4
Homo sapiens Gene: NOMO1
Summary
InnateDB Gene IDBG-15589.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NOMO1
Gene Name NODAL modulator 1
Synonyms Nomo; PM5
Species Homo sapiens
Ensembl Gene ENSG00000103512
Encoded Proteins
IDBP-15591
NODAL modulator 1
IDBP-752172
IDBP-813100
NODAL modulator 1
IDBP-813104
NODAL modulator 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein originally thought to be related to the collagenase gene family. This gene is one of three highly similar genes in a region of duplication located on the p arm of chromosome 16. These three genes encode closely related proteins that may have the same function. The protein encoded by one of these genes has been identified as part of a protein complex that participates in the Nodal signaling pathway during vertebrate development. Mutations in ABCC6, which is located nearby, rather than mutations in this gene are associated with pseudoxanthoma elasticum (PXE). [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:14833681-14896160
Strand Forward strand
Band p13.11
Transcripts
ENST00000287667 ENSP00000287667
ENST00000566917
ENST00000565655 ENSP00000457581
ENST00000566823
ENST00000566883
ENST00000566720
ENST00000610363 ENSP00000479933
ENST00000620755 ENSP00000483827
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
Experimentally validated
Total 21 [view]
Protein-Protein 21 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0030246 carbohydrate binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL Q9H049
UniProt Splice Variant
Entrez Gene 23420
UniGene
RefSeq NM_014287
HUGO HGNC:30060
OMIM 609157
CCDS CCDS10556
HPRD
IMGT
EMBL AL512687
GenPept CAC21645
RNA Seq Atlas 102723728 23420

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca