Version 5.4
Mus musculus Gene: Tep1
Summary
InnateDB Gene IDBG-156406.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tep1
Gene Name telomerase associated protein 1
Synonyms Tp1
Species Mus musculus
Ensembl Gene ENSMUSG00000006281
Encoded Proteins
IDBP-156408
telomerase associated protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000129566:
This gene product is a component of the ribonucleoprotein complex responsible for telomerase activity which catalyzes the addition of new telomeres on the chromosome ends. The telomerase-associated proteins are conserved from ciliates to humans. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:50824062-50870560
Strand Reverse strand
Band C1
Transcripts
ENSMUST00000006444 ENSMUSP00000006444
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003720 telomerase activity
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0005524 ATP binding
Biological Process
GO:0000722 telomere maintenance via recombination
GO:0006278 RNA-dependent DNA replication
Cellular Component
GO:0000781 chromosome, telomeric region
GO:0005697 telomerase holoenzyme complex
GO:0005737 cytoplasm
GO:0016363 nuclear matrix
GO:0030529 ribonucleoprotein complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000129566
View Gene Order
ENSBTAG00000001179
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt P97499
TrEMBL
UniProt Splice Variant
Entrez Gene 21745
UniGene Mm.318736
RefSeq NM_009351 XM_006518797 XM_006518798
OMIM
CCDS CCDS36907
HPRD
IMGT
MGI ID MGI:109573
MGI Symbol Tep1
EMBL U86137
GenPept AAC53043
RNA Seq Atlas 21745

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca