Version 5.4
Mus musculus Gene: Dbc1
Summary
InnateDB Gene IDBG-156775.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dbc1
Gene Name deleted in bladder cancer 1 (human)
Synonyms BRINP; Dbc1; Dbccr1; Fam5a
Species Mus musculus
Ensembl Gene ENSMUSG00000028351
Encoded Proteins
IDBP-156777
deleted in bladder cancer 1 (human)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000078725:
This gene is located within a chromosomal region that shows loss of heterozygosity in some bladder cancers. It contains a 5' CpG island that may be a frequent target of hypermethylation, and it may undergo hypermethylation-based silencing in some bladder cancers. [provided by RefSeq, Jul 2008]
This gene is located within a chromosomal region that shows loss of heterozygosity in some bladder cancers. It contains a 5\' CpG island that may be a frequent target of hypermethylation, and it may undergo hypermethylation-based silencing in some bladder cancers. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:68761514-68954397
Strand Reverse strand
Band C1
Transcripts
ENSMUST00000030036 ENSMUSP00000030036
ENSMUST00000156773
ENSMUST00000140572
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0007050 cell cycle arrest
GO:0008219 cell death
GO:0045666 positive regulation of neuron differentiation
GO:0045786 negative regulation of cell cycle
GO:0045930 negative regulation of mitotic cell cycle
GO:0071300 cellular response to retinoic acid
Cellular Component
GO:0005575 cellular_component
GO:0005737 cytoplasm
GO:0015630 microtubule cytoskeleton
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000078725
View Gene Order
ENSBTAG00000015936
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_2
AndrogenReceptor pathway
NetPath_9
TNFalpha pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt Q920P3
TrEMBL
UniProt Splice Variant
Entrez Gene 56710
UniGene Mm.248788
RefSeq NM_019967
OMIM
CCDS CCDS18272
HPRD
IMGT
MGI ID MGI:1928478
MGI Symbol Brinp1
EMBL AB060587 AB060589 AB088118 AF202896 AK028321 AK045420 BC048789 BC079630 BX088573 BX649413
GenPept AAF17579 AAH48789 AAH79630 BAB70600 BAB70601 BAC25879 BAC32355 BAC55204 CAI24368 CAI26033
RNA Seq Atlas 56710

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca