Mus musculus Gene: Sema5b
Summary
InnateDB Gene IDBG-156960.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sema5b
Gene Name sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
Synonyms AI893641; mKIAA1445; Semag; SemG
Species Mus musculus
Ensembl Gene ENSMUSG00000052133
Encoded Proteins
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000082684:
This gene encodes a member of the semaphorin protein family which regulates axon growth during development of the nervous system. The encoded protein has a characteristic Sema domain near the N-terminus, through which semaphorins bind to plexin, and five thrombospondin type 1 repeats in the C-terminal region of the protein. The protein product may be cleaved and exist as a secreted molecule (PMID: 19463192). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:35541145-35664732
Strand Forward strand
Band B3
Transcripts
ENSMUST00000050625 ENSMUSP00000057494
ENSMUST00000120756 ENSMUSP00000112536
ENSMUST00000133554
ENSMUST00000139805
ENSMUST00000149855 ENSMUSP00000115969
ENSMUST00000149097
ENSMUST00000128347 ENSMUSP00000121703
ENSMUST00000128966
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0005515 protein binding
Biological Process
GO:0007275 multicellular organismal development
GO:0007399 nervous system development
GO:0030154 cell differentiation
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
Axon guidance pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Post-translational protein modification pathway
O-linked glycosylation pathway
Metabolism of proteins pathway
O-glycosylation of TSR domain-containing proteins pathway
KEGG
Axon guidance pathway
INOH
PID NCI
Cross-References
SwissProt Q60519
TrEMBL
UniProt Splice Variant
Entrez Gene 20357
UniGene Mm.42015 Mm.462181
RefSeq NM_013661 XM_006521868 XM_006521867 XM_006521869 XM_006521870
OMIM
CCDS CCDS28140
HPRD
IMGT
MGI ID MGI:107555
MGI Symbol Sema5b
EMBL AC154653 AK078659 AK129362 BC052397 CH466521 CT010576 X97818
GenPept AAH52397 BAC37350 BAC98172 CAA66398 CAP19226 EDK97889
RNA Seq Atlas 20357