InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Tacr2

Summary

InnateDB Gene

IDBG-157009.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tacr2

Gene Name

tachykinin receptor 2

Synonyms

Nk2r; Skr; Tac2r

Species

Mus musculus

Ensembl Gene

ENSMUSG00000020081

Encoded Proteins

IDBP-157011

tachykinin receptor 2

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000075073:
This gene belongs to a family of genes that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5'-end of the sequence. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin neuropeptide substance K, also referred to as neurokinin A. [provided by RefSeq, Jul 2008]
This gene belongs to a family of genes that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5\'-end of the sequence. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin neuropeptide substance K, also referred to as neurokinin A. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 10:62252438-62265990

Strand

Forward strand

Band

Transcripts

ENSMUST00000020278

ENSMUSP00000020278

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004930	G-protein coupled receptor activity
GO:0005515	protein binding
GO:0016497	substance K receptor activity

Biological Process

GO:0007186	G-protein coupled receptor signaling pathway
GO:0007217	tachykinin receptor signaling pathway
GO:0014057	positive regulation of acetylcholine secretion
GO:0014827	intestine smooth muscle contraction
GO:0033685	negative regulation of luteinizing hormone secretion
GO:0035106	operant conditioning
GO:0043117	positive regulation of vascular permeability
GO:0043270	positive regulation of ion transport
GO:0051602	response to electrical stimulus
GO:0070459	prolactin secretion
GO:0070474	positive regulation of uterine smooth muscle contraction