Version 5.4
| Mus musculus Gene: Ggcx | |||||||
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| Summary | |||||||
| InnateDB Gene | IDBG-157282.6 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | Ggcx | ||||||
| Gene Name | gamma-glutamyl carboxylase | ||||||
| Synonyms | |||||||
| Species | Mus musculus | ||||||
| Ensembl Gene | ENSMUSG00000053460 | ||||||
| Encoded Proteins |
gamma-glutamyl carboxylase
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||
| Entrez Gene | |||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000115486:
This gene encodes an enzyme which catalyzes the posttranslational modification of vitamin K-dependent protein. Many of these vitamin K-dependent proteins are involved in coagulation so the function of the encoded enzyme is essential for hemostasis. Mutations in this gene are associated with vitamin K-dependent coagulation defect and PXE-like disorder with multiple coagulation factor deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2008] |
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| Gene Information | |||||||
| Type | Protein coding | ||||||
| Genomic Location | Chromosome 6:72414308-72430712 | ||||||
| Strand | Forward strand | ||||||
| Band | C1 | ||||||
| Transcripts |
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| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||
| NETPATH | |||||||
| REACTOME |
Metabolism of proteins pathway
Post-translational protein modification pathway
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins pathway
Gamma-carboxylation of protein precursors pathway
PTM: gamma carboxylation, hypusine formation and arylsulfatase activation pathway
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| KEGG |
Ubiquinone and other terpenoid-quinone biosynthesis pathway
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| INOH | |||||||
| PID NCI | |||||||
| Pathway Predictions based on Human Orthology Data | |||||||
| NETPATH | |||||||
| REACTOME |
Gamma-carboxylation of protein precursors pathway
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins pathway
Post-translational protein modification pathway
PTM: gamma carboxylation, hypusine formation and arylsulfatase activation pathway
Metabolism of proteins pathway
Gamma-carboxylation of protein precursors pathway
Metabolism of proteins pathway
Post-translational protein modification pathway
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins pathway
PTM: gamma carboxylation, hypusine formation and arylsulfatase activation pathway
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| KEGG |
Ubiquinone and other terpenoid-quinone biosynthesis pathway
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| INOH | |||||||
| PID NCI | |||||||
| Cross-References | |||||||
| SwissProt | Q9QYC7 | ||||||
| TrEMBL | B2RS80 Q8BSR0 | ||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 56316 | ||||||
| UniGene | Mm.19937 Mm.400041 Mm.400367 | ||||||
| RefSeq | NM_019802 XM_006506417 | ||||||
| OMIM | |||||||
| CCDS | CCDS20242 | ||||||
| HPRD | |||||||
| IMGT | |||||||
| MGI ID | MGI:1927655 | ||||||
| MGI Symbol | Ggcx | ||||||
| EMBL | AF087938 AK030779 AK033496 AK036577 AK135425 BC138763 BC138764 CH466523 | ||||||
| GenPept | AAF21291 AAI38764 AAI38765 BAC27134 BAC28319 BAC29487 BAE22528 EDK98981 | ||||||
| RNA Seq Atlas | 56316 | ||||||