Version 5.4
Mus musculus Gene: Upk2
Summary
InnateDB Gene IDBG-157500.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Upk2
Gene Name uroplakin 2
Synonyms AW491716; UPII
Species Mus musculus
Ensembl Gene ENSMUSG00000041523
Encoded Proteins
IDBP-157502
uroplakin 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000110375:
This gene encodes one of the proteins of the highly conserved urothelium-specific integral membrane proteins of the asymmetric unit membrane which forms urothelium apical plaques in mammals. The asymmetric unit membrane is believed to strengthen the urothelium by preventing cell rupture during bladder distention. The encoded protein is expressed in the peripheral blood of bladder cancer patients with transitional cell carcinomas.[provided by RefSeq, Sep 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:44452716-44454767
Strand Reverse strand
Band A5.2
Transcripts
ENSMUST00000047740 ENSMUSP00000040481
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0030855 epithelial cell differentiation
GO:0061024 membrane organization
Cellular Component
GO:0016324 apical plasma membrane
GO:0030176 integral component of endoplasmic reticulum membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000110375
View Gene Order
ENSBTAG00000012750
Not yet available
Cross-References
SwissProt
TrEMBL Q3SXK0
UniProt Splice Variant
Entrez Gene 22269
UniGene Mm.4453
RefSeq NM_009476
OMIM
CCDS CCDS23112
HPRD
IMGT
MGI ID MGI:98913
MGI Symbol Upk2
EMBL AC122428 BC104260 BC104261 CH466522 DQ358978
GenPept AAI04261 AAI04262 ABC86831 EDL25596
RNA Seq Atlas 22269

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca