InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Slc15a2

Summary

InnateDB Gene

IDBG-158269.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Slc15a2

Gene Name

solute carrier family 15 (H+/peptide transporter), member 2

Synonyms

8430408C16Rik; C78862; Pept2

Species

Mus musculus

Ensembl Gene

ENSMUSG00000022899

Encoded Proteins

IDBP-158271

solute carrier family 15 (H+/peptide transporter), member 2

IDBP-622151

solute carrier family 15 (H+/peptide transporter), member 2

IDBP-622153

solute carrier family 15 (H+/peptide transporter), member 2

IDBP-622163

solute carrier family 15 (H+/peptide transporter), member 2

IDBP-622164

solute carrier family 15 (H+/peptide transporter), member 2

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000163406:
The mammalian kidney expresses a proton-coupled peptide transporter that is responsible for the absorption of small peptides, as well as beta-lactam antibiotics and other peptide-like drugs, from the tubular filtrate. This transporter, SLC15A2, belongs to the same gene family as SLC15A1 (MIM 600544), the proton-coupled peptide transporter found in the small intestine (Liu et al, 1995 [PubMed 7756356]).[supplied by OMIM, Feb 2011]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 16:36750178-36784962

Strand

Reverse strand

Band

Transcripts

ENSMUST00000023616	ENSMUSP00000023616
ENSMUST00000100308
ENSMUST00000165380	ENSMUSP00000131395
ENSMUST00000165531	ENSMUSP00000132663
ENSMUST00000163471
ENSMUST00000172382
ENSMUST00000163964
ENSMUST00000167941
ENSMUST00000164770
ENSMUST00000167909
ENSMUST00000164579	ENSMUSP00000132029
ENSMUST00000168279	ENSMUSP00000132885
ENSMUST00000166399
ENSMUST00000169644

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005215	transporter activity
GO:0005515	protein binding
GO:0015198	oligopeptide transporter activity
GO:0015334	high affinity oligopeptide transporter activity
GO:0042895	antibiotic transporter activity
GO:0042936	dipeptide transporter activity

Biological Process

GO:0006810	transport
GO:0006857	oligopeptide transport
GO:0042891	antibiotic transport
GO:0042938	dipeptide transport

Cellular Component

GO:0005887	integral component of plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0070062	extracellular vesicular exosome

Orthologs

Species

Homo sapiens

Bos taurus

Gene ID

Gene Order

ENSG00000163406

View Gene Order

ENSBTAG00000033166

Not yet available

Pathway Predictions based on Human Orthology Data

NETPATH

REACTOME

REACT_19328

Proton/oligonucleotide cotransporters pathway

REACT_19397

Transport of inorganic cations/anions and amino acids/oligopeptides pathway

REACT_15518

Transmembrane transport of small molecules pathway

REACT_19118

SLC-mediated transmembrane transport pathway

KEGG

INOH

PID NCI

Cross-References

SwissProt

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

Mm.281804 Mm.404463

RefSeq

NM_001145899 NM_021301 XM_006522428 XM_006522430

OMIM

CCDS

CCDS28156 CCDS49842

HPRD

IMGT

MGI ID

MGI Symbol

EMBL

GenPept

RNA Seq Atlas