Version 5.4
Mus musculus Gene: Insrr
Summary
InnateDB Gene IDBG-158706.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Insrr
Gene Name insulin receptor-related receptor
Synonyms Irr
Species Mus musculus
Ensembl Gene ENSMUSG00000005640
Encoded Proteins
IDBP-158708
insulin receptor-related receptor
IDBP-266352
insulin receptor-related receptor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000027644:
Gene Information
Type Protein coding
Genomic Location Chromosome 3:87796951-87816101
Strand Forward strand
Band F1
Transcripts
ENSMUST00000029711 ENSMUSP00000029711
ENSMUST00000107582 ENSMUSP00000103208
ENSMUST00000166771
ENSMUST00000166866
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0043548 phosphatidylinositol 3-kinase binding
GO:0043560 insulin receptor substrate binding
Biological Process
GO:0006468 protein phosphorylation
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0018108 peptidyl-tyrosine phosphorylation
GO:0030238 male sex determination
GO:0031532 actin cytoskeleton reorganization
GO:0046777 protein autophosphorylation
GO:0071469 cellular response to alkalinity
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0043235 receptor complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000027644
View Gene Order
ENSBTAG00000003054
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04810
Regulation of actin cytoskeleton pathway
mmu05215
Prostate cancer pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04810
Regulation of actin cytoskeleton pathway
hsa05215
Prostate cancer pathway
INOH
PID NCI
Cross-References
SwissProt Q9WTL4
TrEMBL Q3UWD6 Q8C4P9
UniProt Splice Variant
Entrez Gene 23920
UniGene Mm.42041
RefSeq NM_011832 XM_006501453 XM_006501454
OMIM
CCDS CCDS17454
HPRD
IMGT
MGI ID MGI:1346037
MGI Symbol Insrr
EMBL AB007135 AK081512 AK136441 BC137855 CH466547
GenPept AAI37856 BAA77835 BAC38244 BAE22979 EDL15346
RNA Seq Atlas 23920

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca