Version 5.4
Mus musculus Gene: Prcc
Summary
InnateDB Gene IDBG-158923.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Prcc
Gene Name papillary renal cell carcinoma (translocation-associated)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000004895
Encoded Proteins
IDBP-158925
papillary renal cell carcinoma (translocation-associated)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143294:
This gene encodes a protein that may play a role in pre-mRNA splicing. Chromosomal translocations (X;1)(p11;q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle.[provided by RefSeq, Aug 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:87858900-87885608
Strand Reverse strand
Band F1
Transcripts
ENSMUST00000005015 ENSMUSP00000005015
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 0
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0007093 mitotic cell cycle checkpoint
Cellular Component
GO:0005634 nucleus
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000143294
View Gene Order
ENSBTAG00000000608
Not yet available
Cross-References
SwissProt
TrEMBL Q9EQC8
UniProt Splice Variant
Entrez Gene 94315
UniGene Mm.35089
RefSeq NM_033573
OMIM
CCDS CCDS17456
HPRD
IMGT
MGI ID MGI:2137738
MGI Symbol Prcc
EMBL AC158233 AC161454 AF273750 AK078394 BC052072 BC082784 CH466547
GenPept AAG36941 AAH52072 AAH82784 BAC37252 EDL15343
RNA Seq Atlas 94315

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca