Mus musculus Gene: Lipf
Summary
InnateDB Gene IDBG-159099.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lipf
Gene Name lipase, gastric
Synonyms 2310051B21Rik; AV082900
Species Mus musculus
Ensembl Gene ENSMUSG00000024768
Encoded Proteins
lipase, gastric
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000182333:
This gene encodes gastric lipase, an enzyme involved in the digestion of dietary triglycerides in the gastrointestinal tract, and responsible for 30% of fat digestion processes occurring in human. It is secreted by gastric chief cells in the fundic mucosa of the stomach, and it hydrolyzes the ester bonds of triglycerides under acidic pH conditions. The gene is a member of a conserved gene family of lipases that play distinct roles in neutral lipid metabolism. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
This gene encodes gastric lipase, an enzyme involved in the digestion of dietary triglycerides in the gastrointestinal tract, and responsible for 30%% of fat digestion processes occurring in human. It is secreted by gastric chief cells in the fundic mucosa of the stomach, and it hydrolyzes the ester bonds of triglycerides under acidic pH conditions. The gene is a member of a conserved gene family of lipases that play distinct roles in neutral lipid metabolism. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:33961187-33976810
Strand Forward strand
Band C1
Transcripts
ENSMUST00000025680 ENSMUSP00000025680
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004806 triglyceride lipase activity
GO:0016615 malate dehydrogenase activity
Biological Process
GO:0006108 malate metabolic process
GO:0006629 lipid metabolic process
GO:0016042 lipid catabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005575 cellular_component
GO:0005576 extracellular region
GO:0005739 mitochondrion
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
Pathways
NETPATH
REACTOME
KEGG
Glycerolipid metabolism pathway
Fat digestion and absorption pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
Glycerolipid metabolism pathway
Fat digestion and absorption pathway
INOH
PID NCI
Cross-References
SwissProt Q9CPP7
TrEMBL
UniProt Splice Variant
Entrez Gene 67717
UniGene Mm.329816
RefSeq NM_026334
OMIM
CCDS CCDS29754
HPRD
IMGT
MGI ID MGI:1914967
MGI Symbol Lipf
EMBL AK009300 AK009359 AK009413 AK009428 AK009431 AK009437 AK009459 AK009473 AK009474 AK009479 AK009523 AK009525 AK009537 AK009544 AK009546 AK009560 AK009571 AK009573 AK009729 AK009773 AK009875 AK009990 AK010019 AK010026 AK010035 AK010058 AK010061 AK010093 AK010103 AK010106 AK010116 AK010124 AK010125 AK010139 AK010148 AK010173 AK010203 AK010231 AK010236 AK075910 BC061067
GenPept AAH61067 BAB26201 BAB26240 BAB26272 BAB26280 BAB26283 BAB26287 BAB26300 BAB26312 BAB26313 BAB26316 BAB26338 BAB26339 BAB26346 BAB26350 BAB26352 BAB26359 BAB26368 BAB26370 BAB26466 BAB26495 BAB26556 BAB26629 BAB26647 BAB26651 BAB26656 BAB26673 BAB26675 BAB26697 BAB26703 BAB26704 BAB26711 BAB26715 BAB26716 BAB26725 BAB26733 BAB26746 BAB26766 BAB26784 BAB26787 BAC36048
RNA Seq Atlas 67717