Version 5.4
Mus musculus Gene: Ift43
Summary
InnateDB Gene IDBG-159112.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ift43
Gene Name intraflagellar transport 43 homolog (Chlamydomonas)
Synonyms 1700019E19Rik; R75064
Species Mus musculus
Ensembl Gene ENSMUSG00000007867
Encoded Proteins
IDBP-159114
RIKEN cDNA 1700019E19 gene
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000119650:
This gene encodes a subunit of the intraflagellar transport complex A (IFT-A). IFT-A is a multiprotein complex that plays an important role in cilia assembly and maintenance by mediating retrograde ciliary transport. Mutations in this gene are a cause of cranioectodermal dysplasia-3 (CED3), also known as Sensenbrenner syndrome. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:86082561-86162458
Strand Forward strand
Band D2
Transcripts
ENSMUST00000054565 ENSMUSP00000061891
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0035721 intraciliary retrograde transport
GO:0060271 cilium morphogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0005815 microtubule organizing center
GO:0005856 cytoskeleton
GO:0015630 microtubule cytoskeleton
GO:0030991 intraciliary transport particle A
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000119650
View Gene Order
ENSBTAG00000012005
Not yet available
Cross-References
SwissProt Q9DA69
TrEMBL
UniProt Splice Variant
Entrez Gene 76411
UniGene
RefSeq NM_001199843 NM_029601
OMIM
CCDS CCDS26064
HPRD
IMGT
MGI ID MGI:1923661
MGI Symbol Ift43
EMBL AK006115 BC034668 BC038915
GenPept AAH34668 AAH38915 BAB24415
RNA Seq Atlas 76411

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca