Mus musculus Gene: Il9r
Summary
InnateDB Gene IDBG-159548.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Il9r
Gene Name interleukin 9 receptor
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000020279
Encoded Proteins
interleukin 9 receptor
interleukin 9 receptor
interleukin 9 receptor
interleukin 9 receptor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog null:
The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic responses. This gene is located at the pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested an association of this gene with the development of asthma. Multiple pseudogenes on chromosome 9, 10, 16, and 18 have been described. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:32187541-32200279
Strand Reverse strand
Band A4
Transcripts
ENSMUST00000020518 ENSMUSP00000020518
ENSMUST00000145401 ENSMUSP00000118204
ENSMUST00000128311 ENSMUSP00000119557
ENSMUST00000142396 ENSMUSP00000119185
ENSMUST00000131979
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004896 cytokine receptor activity
GO:0004919 interleukin-9 receptor activity
GO:0005515 protein binding
GO:0019983 interleukin-9 binding
Biological Process
GO:0019221 cytokine-mediated signaling pathway
GO:0030307 positive regulation of cell growth
GO:0038113 interleukin-9-mediated signaling pathway
Cellular Component
GO:0005576 extracellular region
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Bos taurus
Homo sapiens
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
Cytokine-cytokine receptor interaction pathway
Jak-STAT signaling pathway pathway
Hematopoietic cell lineage pathway
INOH
JAK STAT pathway and regulation pathway
PID NCI
Cross-References
SwissProt Q01114
TrEMBL Q78PA5
UniProt Splice Variant
Entrez Gene 16199
UniGene Mm.383776 Mm.384
RefSeq NM_008374 XM_006514535 XM_006514536 XM_006514537 XM_006514538 NM_001134458 XM_006514539
OMIM
CCDS CCDS24517 CCDS48765
HPRD
IMGT
MGI ID MGI:96564
MGI Symbol Il9r
EMBL AY016021 M84746
GenPept AAA37871 AAL32365
RNA Seq Atlas 16199