Version 5.4
| Mus musculus Gene: Fxyd6 | |||||||
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| Summary | |||||||
| InnateDB Gene | IDBG-159611.6 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | Fxyd6 | ||||||
| Gene Name | FXYD domain-containing ion transport regulator 6 | ||||||
| Synonyms | 0610030I18Rik; Php | ||||||
| Species | Mus musculus | ||||||
| Ensembl Gene | ENSMUSG00000066705 | ||||||
| Encoded Proteins |
FXYD domain-containing ion transport regulator 6
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||
| Entrez Gene | |||||||
| Summary |
This reference sequence was derived from multiple replicate ESTs and validated by similar human genomic sequence. This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. This gene product, Fxyd6, is novel and has not been characterized as a protein. [RefSeq curation by Kathleen J. Sweadner, Ph.D., sweadner@helix.mgh.harvard.edu., Jul 2006] |
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| Gene Information | |||||||
| Type | Protein coding | ||||||
| Genomic Location | Chromosome 9:45370185-45396158 | ||||||
| Strand | Forward strand | ||||||
| Band | A5.2 | ||||||
| Transcripts |
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| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||
| NETPATH | |||||||
| REACTOME |
Ion channel transport pathway
Transmembrane transport of small molecules pathway
Ion transport by P-type ATPases pathway
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| KEGG | |||||||
| INOH | |||||||
| PID NCI | |||||||
| Pathway Predictions based on Human Orthology Data | |||||||
| NETPATH | |||||||
| REACTOME |
Ion transport by P-type ATPases pathway
Transmembrane transport of small molecules pathway
Ion channel transport pathway
Ion channel transport pathway
Transmembrane transport of small molecules pathway
Ion transport by P-type ATPases pathway
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| KEGG | |||||||
| INOH | |||||||
| PID NCI | |||||||
| Cross-References | |||||||
| SwissProt | Q9D164 | ||||||
| TrEMBL | |||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 59095 | ||||||
| UniGene | Mm.474649 | ||||||
| RefSeq | NM_022004 XM_006510521 XM_006510522 | ||||||
| OMIM | |||||||
| CCDS | CCDS23133 | ||||||
| HPRD | |||||||
| IMGT | |||||||
| MGI ID | MGI:1890226 | ||||||
| MGI Symbol | Fxyd6 | ||||||
| EMBL | AB032010 AK003888 AK018354 BC042579 BC051127 | ||||||
| GenPept | AAH42579 AAH51127 BAB23058 BAB31174 BAB40451 | ||||||
| RNA Seq Atlas | 59095 | ||||||