Version 5.4
Homo sapiens Gene: PKD1L1
Summary
InnateDB Gene IDBG-15982.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PKD1L1
Gene Name polycystic kidney disease 1 like 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000158683
Encoded Proteins
IDBP-15984
polycystic kidney disease 1 like 1
IDBP-374930
polycystic kidney disease 1 like 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the polycystin protein family containing 11 transmembrane domains, a receptor for egg jelly (REJ) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. The encoded protein may play a role in the male reproductive system. Alternative splice variants have been described but their biological nature has not been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:47774652-47948491
Strand Reverse strand
Band p12.3
Transcripts
ENST00000289672 ENSP00000289672
ENST00000433506 ENSP00000393466
ENST00000483616
ENST00000462350
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005262 calcium channel activity
GO:0005515 protein binding
Biological Process
GO:0003127 detection of nodal flow
GO:0016337 single organismal cell-cell adhesion
GO:0050982 detection of mechanical stimulus
GO:0070588 calcium ion transmembrane transport
GO:0070986 left/right axis specification
Cellular Component
GO:0005929 cilium
GO:0016020 membrane
GO:0031513 nonmotile primary cilium
GO:0034704 calcium channel complex
GO:0060170 ciliary membrane
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000046634
View Gene Order
Cross-References
SwissProt Q8TDX9
TrEMBL
UniProt Splice Variant
Entrez Gene 168507
UniGene Hs.195979
RefSeq NM_138295
HUGO HGNC:18053
OMIM 609721
CCDS CCDS34633
HPRD 10154
IMGT
EMBL AB061683 AY358757
GenPept AAQ89117 BAB85807
RNA Seq Atlas 168507

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca