Version 5.4
Mus musculus Gene: Rhobtb1
Summary
InnateDB Gene IDBG-160325.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rhobtb1
Gene Name Rho-related BTB domain containing 1
Synonyms 1700008H16Rik; 3110048G13Rik; AI173445; AI573858; AV350930
Species Mus musculus
Ensembl Gene ENSMUSG00000019944
Encoded Proteins
IDBP-160327
Rho-related BTB domain containing 1
IDBP-160329
Rho-related BTB domain containing 1
IDBP-626036
Rho-related BTB domain containing 1
IDBP-626040
Rho-related BTB domain containing 1
IDBP-626044
Rho-related BTB domain containing 1
IDBP-626047
Rho-related BTB domain containing 1
IDBP-626048
Rho-related BTB domain containing 1
IDBP-626054
Rho-related BTB domain containing 1
IDBP-626056
Rho-related BTB domain containing 1
IDBP-626057
Rho-related BTB domain containing 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000072422:
The protein encoded by this gene belongs to the Rho family of the small GTPase superfamily. It contains a GTPase domain, a proline-rich region, a tandem of 2 BTB (broad complex, tramtrack, and bric-a-brac) domains, and a conserved C-terminal region. The protein plays a role in small GTPase-mediated signal transduction and the organization of the actin filament system. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:69151434-69291791
Strand Forward strand
Band B5.3
Transcripts
ENSMUST00000020101 ENSMUSP00000020101
ENSMUST00000067908 ENSMUSP00000065095
ENSMUST00000167286 ENSMUSP00000131313
ENSMUST00000164034 ENSMUSP00000132068
ENSMUST00000164876
ENSMUST00000167384 ENSMUSP00000131222
ENSMUST00000163497 ENSMUSP00000129119
ENSMUST00000164212 ENSMUSP00000128356
ENSMUST00000168117 ENSMUSP00000131509
ENSMUST00000172261 ENSMUSP00000128667
ENSMUST00000169569
ENSMUST00000163760 ENSMUSP00000127904
ENSMUST00000165765
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005525 GTP binding
Biological Process
GO:0006184 GTP catabolic process
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0015031 protein transport
Cellular Component
GO:0005575 cellular_component
GO:0005622 intracellular
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000072422
View Gene Order
ENSBTAG00000019164
Not yet available
Pathways
NETPATH
REACTOME
REACT_206918
Signaling by Rho GTPases pathway
REACT_210090
Rho GTPase cycle pathway
REACT_188257
Signal Transduction pathway
KEGG
mmu04120
Ubiquitin mediated proteolysis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_11051
Rho GTPase cycle pathway
REACT_11044
Signaling by Rho GTPases pathway
REACT_111102
Signal Transduction pathway
KEGG
hsa04120
Ubiquitin mediated proteolysis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F6UIH6
UniProt Splice Variant
Entrez Gene 69288
UniGene
RefSeq NM_001081347 NM_001252636 NM_001252637 NM_001252638 XM_006514048 XM_006514049 XM_006514050 XM_006514051 XM_006514052 XM_006514053 XM_006514054
OMIM
CCDS CCDS35930
HPRD
IMGT
MGI ID MGI:1916538
MGI Symbol Rhobtb1
EMBL AC117209 AC124503
GenPept
RNA Seq Atlas 69288

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca