Mus musculus Gene: Arhgef9 | |||||||||
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Summary | |||||||||
InnateDB Gene | IDBG-160486.6 | ||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
Gene Symbol | Arhgef9 | ||||||||
Gene Name | CDC42 guanine nucleotide exchange factor (GEF) 9 | ||||||||
Synonyms | |||||||||
Species | Mus musculus | ||||||||
Ensembl Gene | ENSMUSG00000025656 | ||||||||
Encoded Proteins |
CDC42 guanine nucleotide exchange factor (GEF) 9
CDC42 guanine nucleotide exchange factor (GEF) 9
CDC42 guanine nucleotide exchange factor (GEF) 9
CDC42 guanine nucleotide exchange factor (GEF) 9
CDC42 guanine nucleotide exchange factor (GEF) 9
CDC42 guanine nucleotide exchange factor (GEF) 9
CDC42 guanine nucleotide exchange factor (GEF) 9
CDC42 guanine nucleotide exchange factor (GEF) 9
CDC42 guanine nucleotide exchange factor (GEF) 9
CDC42 guanine nucleotide exchange factor (GEF) 9
CDC42 guanine nucleotide exchange factor (GEF) 9
CDC42 guanine nucleotide exchange factor (GEF) 9
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Protein Structure | |||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||
Entrez Gene | |||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000131089:
The protein encoded by this gene is a Rho-like GTPase that switches between the active (GTP-bound) state and inactive (GDP-bound) state to regulate CDC42 and other genes. Defects in this gene are a cause of startle disease with epilepsy (STHEE), also known as hyperekplexia with epilepsy. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010] |
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Gene Information | |||||||||
Type | Protein coding | ||||||||
Genomic Location | Chromosome X:95048935-95196821 | ||||||||
Strand | Reverse strand | ||||||||
Band | C3 | ||||||||
Transcripts | |||||||||
Interactions | |||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||
NETPATH | |||||||||
REACTOME |
GPCR downstream signaling pathway
GABA A receptor activation pathway
Signaling by GPCR pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
Orphan transporters pathway
NRAGE signals death through JNK pathway
Ligand-gated ion channel transport pathway
Signaling by Rho GTPases pathway
Cell death signalling via NRAGE, NRIF and NADE pathway
G alpha (12/13) signalling events pathway
Ion channel transport pathway
Rho GTPase cycle pathway
Transmembrane transport of small molecules pathway
GABA receptor activation pathway
Signalling by NGF pathway
Neuronal System pathway
Signal Transduction pathway
p75 NTR receptor-mediated signalling pathway
Transmission across Chemical Synapses pathway
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KEGG | |||||||||
INOH | |||||||||
PID NCI | |||||||||
Pathway Predictions based on Human Orthology Data | |||||||||
NETPATH | |||||||||
REACTOME |
Ligand-gated ion channel transport pathway
NRAGE signals death through JNK pathway
G alpha (12/13) signalling events pathway
Rho GTPase cycle pathway
GABA A receptor activation pathway
Transmembrane transport of small molecules pathway
Signalling by NGF pathway
Signaling by Rho GTPases pathway
Neuronal System pathway
Signaling by GPCR pathway
GABA receptor activation pathway
p75 NTR receptor-mediated signalling pathway
Signal Transduction pathway
GPCR downstream signaling pathway
Orphan transporters pathway
Ion channel transport pathway
Transmission across Chemical Synapses pathway
Cell death signalling via NRAGE, NRIF and NADE pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
Orphan transporters pathway
Signaling by GPCR pathway
Ion channel transport pathway
GABA receptor activation pathway
Transmission across Chemical Synapses pathway
Transmembrane transport of small molecules pathway
Cell death signalling via NRAGE, NRIF and NADE pathway
Rho GTPase cycle pathway
Signal Transduction pathway
Signaling by Rho GTPases pathway
Ligand-gated ion channel transport pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
NRAGE signals death through JNK pathway
GPCR downstream signaling pathway
Neuronal System pathway
Signalling by NGF pathway
G alpha (12/13) signalling events pathway
GABA A receptor activation pathway
p75 NTR receptor-mediated signalling pathway
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KEGG | |||||||||
INOH | |||||||||
PID NCI |
Regulation of CDC42 activity
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Cross-References | |||||||||
SwissProt | |||||||||
TrEMBL | |||||||||
UniProt Splice Variant | |||||||||
Entrez Gene | |||||||||
UniGene | Mm.397652 Mm.408361 Mm.44841 | ||||||||
RefSeq | NM_001033329 NM_001290384 NM_001290385 XM_006527992 XM_006527993 | ||||||||
OMIM | |||||||||
CCDS | CCDS53137 CCDS72409 | ||||||||
HPRD | |||||||||
IMGT | |||||||||
MGI ID | |||||||||
MGI Symbol | |||||||||
EMBL | |||||||||
GenPept | |||||||||
RNA Seq Atlas | |||||||||