Version 5.4
Mus musculus Gene: Asb12
Summary
InnateDB Gene IDBG-160555.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Asb12
Gene Name ankyrin repeat and SOCS box-containing 12
Synonyms 2310036C05Rik; Asb-12
Species Mus musculus
Ensembl Gene ENSMUSG00000031204
Encoded Proteins
IDBP-160557
ankyrin repeat and SOCS box-containing 12
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000198881:
The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. [provided by RefSeq, Jan 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome X:95470201-95478129
Strand Reverse strand
Band C3
Transcripts
ENSMUST00000033549 ENSMUSP00000033549
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
GO:0016567 protein ubiquitination
GO:0035556 intracellular signal transduction
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000198881
View Gene Order
ENSBTAG00000007211
Not yet available
Pathways
NETPATH
REACTOME
REACT_236645
Class I MHC mediated antigen processing & presentation pathway
REACT_230745
Immune System pathway
REACT_199115
Antigen processing: Ubiquitination & Proteasome degradation pathway
REACT_229531
Adaptive Immune System pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_75842
Antigen processing: Ubiquitination & Proteasome degradation pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
REACT_75820
Class I MHC mediated antigen processing & presentation pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q9D738
TrEMBL Q3KNI9
UniProt Splice Variant
Entrez Gene 70392
UniGene Mm.79122
RefSeq NM_080858 XM_006528277
OMIM
CCDS CCDS30283
HPRD
IMGT
MGI ID MGI:1917642
MGI Symbol Asb12
EMBL AF403040 AK009644 BC107257 CH466564
GenPept AAI07258 AAL57359 BAB26410 EDL14232
RNA Seq Atlas 70392

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca