Version 5.4
Mus musculus Gene: Slc4a5
Summary
InnateDB Gene IDBG-160683.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc4a5
Gene Name solute carrier family 4, sodium bicarbonate cotransporter, member 5
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000068323
Encoded Proteins
IDBP-160685
solute carrier family 4, sodium bicarbonate cotransporter, member 5
IDBP-252896
solute carrier family 4, sodium bicarbonate cotransporter, member 5
IDBP-252898
solute carrier family 4, sodium bicarbonate cotransporter, member 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000188687:
This gene encodes a member of the sodium bicarbonate cotransporter (NBC) family, part of the bicarbonate transporter superfamily. Sodium bicarbonate cotransporters are involved in intracellular pH regulation and electroneural or electrogenic sodium bicarbonate transport. This protein is thought to be an integral membrane protein. Multiple transcript variants encoding different isoforms have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:83219828-83304945
Strand Forward strand
Band C3
Transcripts
ENSMUST00000039212 ENSMUSP00000041007
ENSMUST00000113900 ENSMUSP00000109533
ENSMUST00000113899 ENSMUSP00000109532
ENSMUST00000122897
ENSMUST00000141863
ENSMUST00000131432
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005215 transporter activity
GO:0005452 inorganic anion exchanger activity
GO:0008509 anion transmembrane transporter activity
Biological Process
GO:0002064 epithelial cell development
GO:0003014 renal system process
GO:0003073 regulation of systemic arterial blood pressure
GO:0006810 transport
GO:0006811 ion transport
GO:0006820 anion transport
GO:0010468 regulation of gene expression
GO:0033326 cerebrospinal fluid secretion
GO:0048311 mitochondrion distribution
GO:0060041 retina development in camera-type eye
Cellular Component
GO:0005575 cellular_component
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000188687
View Gene Order
ENSBTAG00000004884
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04976
Bile secretion pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_19298
Bicarbonate transporters pathway
REACT_19397
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
hsa04976
Bile secretion pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL D3YX36
UniProt Splice Variant
Entrez Gene 232156
UniGene Mm.333189
RefSeq XM_006505968 NM_001166067 XM_006505965 XM_006505967
OMIM
CCDS CCDS51819
HPRD
IMGT
MGI ID MGI:2443220
MGI Symbol Slc4a5
EMBL AC159713 AC160400
GenPept
RNA Seq Atlas 232156

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca