Version 5.4
Mus musculus Gene: Pbx4
Summary
InnateDB Gene IDBG-160818.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pbx4
Gene Name pre B cell leukemia homeobox 4
Synonyms 2410015M21Rik; AI429113; AW045266
Species Mus musculus
Ensembl Gene ENSMUSG00000031860
Encoded Proteins
IDBP-160820
pre-B-cell leukemia homeobox 4
IDBP-539878
pre-B-cell leukemia homeobox 4
IDBP-540587
pre-B-cell leukemia homeobox 4
IDBP-542184
pre-B-cell leukemia homeobox 4
IDBP-537414
pre-B-cell leukemia homeobox 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000105717:
This gene encodes a member of the pre-B cell leukemia transcription factor family. These proteins are homeobox proteins that play critical roles in embryonic development and cellular differentiation both as Hox cofactors and through Hox-independent pathways. The encoded protein contains a homeobox DNA-binding domain, but specific functions of the protein have not been determined. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:69832491-69872292
Strand Forward strand
Band B3.3
Transcripts
ENSMUST00000081503 ENSMUSP00000080219
ENSMUST00000151975
ENSMUST00000156319 ENSMUSP00000119526
ENSMUST00000134777 ENSMUSP00000122281
ENSMUST00000131637 ENSMUSP00000121369
ENSMUST00000132899 ENSMUSP00000118287
ENSMUST00000132259
ENSMUST00000156251
ENSMUST00000135952
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component
GO:0001741 XY body
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000105717
View Gene Order
Cross-References
SwissProt
TrEMBL D3Z318
UniProt Splice Variant
Entrez Gene 80720
UniGene Mm.210823
RefSeq NM_001024954 XM_006509802 XM_006509803
OMIM
CCDS CCDS22352
HPRD
IMGT
MGI ID MGI:1931321
MGI Symbol Pbx4
EMBL AC158564
GenPept
RNA Seq Atlas 80720

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca