Version 5.4
Mus musculus Gene: Olfr49
Summary
InnateDB Gene IDBG-160946.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Olfr49
Gene Name olfactory receptor 49
Synonyms IC6; MOR1181
Species Mus musculus
Ensembl Gene ENSMUSG00000048153
Encoded Proteins
IDBP-160948
olfactory receptor 49
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:54281896-54282925
Strand Reverse strand
Band C2
Transcripts
ENSMUST00000059996 ENSMUSP00000054361
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0004984 olfactory receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007608 sensory perception of smell
GO:0050911 detection of chemical stimulus involved in sensory perception of smell
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_223625
GPCR downstream signaling pathway
REACT_254215
Signaling by GPCR pathway
REACT_252270
Olfactory Signaling Pathway pathway
REACT_188257
Signal Transduction pathway
KEGG
mmu04740
Olfactory transduction pathway
INOH
PID NCI
Cross-References
SwissProt Q9Z1V0
TrEMBL
UniProt Splice Variant
Entrez Gene 18348
UniGene Mm.436623
RefSeq NM_010991
OMIM
CCDS CCDS27085
HPRD
IMGT
MGI ID MGI:1333764
MGI Symbol Olfr49
EMBL AF102523 AY073614 AY318614 BC145891 BC145893 CH466535 CT573018
GenPept AAD13315 AAI45892 AAI45894 AAL61277 AAP71780 EDL36361
RNA Seq Atlas 18348

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca