Version 5.4
Mus musculus Gene: Kcnmb1
Summary
InnateDB Gene IDBG-161422.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Kcnmb1
Gene Name potassium large conductance calcium-activated channel, subfamily M, beta member 1
Synonyms BKbeta1
Species Mus musculus
Ensembl Gene ENSMUSG00000020155
Encoded Proteins
IDBP-161424
potassium large conductance calcium-activated channel, subfamily M, beta member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000145936:
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the product of this gene, the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:33963013-33973641
Strand Forward strand
Band A4
Transcripts
ENSMUST00000020362 ENSMUSP00000020362
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0015269 calcium-activated potassium channel activity
GO:0015459 potassium channel regulator activity
Biological Process
GO:0006813 potassium ion transport
GO:0051592 response to calcium ion
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0008076 voltage-gated potassium channel complex
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000145936
View Gene Order
ENSBTAG00000002985
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04270
Vascular smooth muscle contraction pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_23767
cGMP effects pathway
REACT_23862
Nitric oxide stimulates guanylate cyclase pathway
REACT_23876
Platelet homeostasis pathway
REACT_75896
Ca2+ activated K+ channels pathway
REACT_13685
Neuronal System pathway
REACT_75908
Potassium Channels pathway
REACT_604
Hemostasis pathway
REACT_223715
Ca2+ activated K+ channels pathway
REACT_225032
Neuronal System pathway
REACT_212420
Potassium Channels pathway
KEGG
hsa04270
Vascular smooth muscle contraction pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL Q5SQK1
UniProt Splice Variant
Entrez Gene 16533
UniGene Mm.6206
RefSeq NM_031169 XM_006514541
OMIM
CCDS CCDS24538
HPRD
IMGT
MGI ID MGI:1334203
MGI Symbol Kcnmb1
EMBL AL731867 CH466604
GenPept EDL23733
RNA Seq Atlas 16533

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca