Version 5.4
Homo sapiens Gene: ZPBP
Summary
InnateDB Gene IDBG-16327.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZPBP
Gene Name zona pellucida binding protein
Synonyms ZPBP1
Species Homo sapiens
Ensembl Gene ENSG00000042813
Encoded Proteins
IDBP-16329
zona pellucida binding protein
IDBP-375148
zona pellucida binding protein
IDBP-375153
zona pellucida binding protein
IDBP-375156
zona pellucida binding protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary ZPBP is one of several proteins that are thought to participate in secondary binding between acrosome-reacted sperm and the egg-specific extracellular matrix, the zona pellucida (McLeskey et al., 1998 [PubMed 9378618]).[supplied by OMIM, Aug 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:49850421-50121329
Strand Reverse strand
Band p12.2
Transcripts
ENST00000046087 ENSP00000046087
ENST00000419417 ENSP00000402071
ENST00000450231 ENSP00000390054
ENST00000413331 ENSP00000414755
ENST00000491129
ENST00000465922
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0001675 acrosome assembly
GO:0007339 binding of sperm to zona pellucida
Cellular Component
GO:0001669 acrosomal vesicle
GO:0002199 zona pellucida receptor complex
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0044297 cell body
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000020193
View Gene Order
ENSBTAG00000005499
Not yet available
Cross-References
SwissProt
TrEMBL F8WDW2
UniProt Splice Variant
Entrez Gene 11055
UniGene Hs.388841 Hs.606870 Hs.730437
RefSeq NM_001159878 NM_007009
HUGO HGNC:15662
OMIM 608498
CCDS CCDS5509 CCDS55110
HPRD 18364
IMGT
EMBL AC020743 AC034145 AC034148 AC096568
GenPept
RNA Seq Atlas 11055

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca