Mus musculus Gene: Bco2
Summary
InnateDB Gene IDBG-163405.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Bco2
Gene Name beta-carotene oxygenase 2
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000032066
Encoded Proteins
beta-carotene oxygenase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000197580:
This gene encodes an enzyme which oxidizes carotenoids such as beta-carotene during the biosynthesis of vitamin A. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:50533087-50555181
Strand Reverse strand
Band A5.3
Transcripts
ENSMUST00000119103 ENSMUSP00000112727
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0046872 metal ion binding
Biological Process
GO:0016116 carotenoid metabolic process
GO:0016119 carotene metabolic process
GO:0016121 carotene catabolic process
GO:0042573 retinoic acid metabolic process
GO:0042574 retinal metabolic process
GO:0051881 regulation of mitochondrial membrane potential
GO:0055114 oxidation-reduction process
GO:2000377 regulation of reactive oxygen species metabolic process
Cellular Component
GO:0005622 intracellular
GO:0005739 mitochondrion
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Disease pathway
Retinoid metabolism and transport pathway
Visual phototransduction pathway
Signal Transduction pathway
Diseases associated with visual transduction pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Retinoid metabolism and transport pathway
Signal Transduction pathway
Diseases associated with visual transduction pathway
Visual phototransduction pathway
Disease pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q99NF1
TrEMBL Q3KNZ2
UniProt Splice Variant
Entrez Gene 170752
UniGene Mm.390149
RefSeq NM_133217 XM_006510044 XM_006510045 XM_006510046
OMIM
CCDS CCDS40620
HPRD
IMGT
MGI ID MGI:2177469
MGI Symbol Bco2
EMBL AJ290392 BC107006 BC107007 CH466522
GenPept AAI07007 AAI07008 CAC28026 EDL25739
RNA Seq Atlas 170752