InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Alms1

Summary

InnateDB Gene

IDBG-163748.7

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Alms1

Gene Name

Alstrom syndrome 1

Synonyms

Species

Mus musculus

Ensembl Gene

ENSMUSG00000063810

Encoded Proteins

IDBP-163750

Alstrom syndrome 1 homolog (human)

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000116127:
This gene encodes a protein containing a large tandem-repeat domain. The mouse ortholog of this gene has been shown to function in ciliogenesis in inner medullary collecting duct cells. Mutations in this gene have been associated with Alstrom syndrome. Alternative splice variants have been described but their full length sequences have not been determined.[provided by RefSeq, Mar 2009]
This gene encodes a protein containing a large tandem-repeat domain as well as additional low complexity regions. The encoded protein functions in microtubule organization, particularly in the formation and maintanance of cilia. Mutations in this gene cause Alstrom syndrome. There is a pseudogene for this gene located adjacent in the same region of chromosome 2. Alternative splice variants have been described but their full length nature has not been determined. [provided by RefSeq, Apr 2014]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 6:85587531-85702753

Strand

Forward strand

Band

Transcripts

ENSMUST00000072018

ENSMUSP00000071904

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.