Version 5.4
Mus musculus Gene: Dcaf11
Summary
InnateDB Gene IDBG-163992.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dcaf11
Gene Name DDB1 and CUL4 associated factor 11
Synonyms 0710008A13Rik; C76035; D14Ucla1; Dacf11; GLO14; Wdr23
Species Mus musculus
Ensembl Gene ENSMUSG00000022214
Encoded Proteins
IDBP-163994
DDB1 and CUL4 associated factor 11
IDBP-401206
DDB1 and CUL4 associated factor 11
IDBP-401204
DDB1 and CUL4 associated factor 11
IDBP-401205
DDB1 and CUL4 associated factor 11
IDBP-537733
DDB1 and CUL4 associated factor 11
IDBP-538757
DDB1 and CUL4 associated factor 11
IDBP-537008
DDB1 and CUL4 associated factor 11
IDBP-539546
DDB1 and CUL4 associated factor 11
IDBP-539499
DDB1 and CUL4 associated factor 11
IDBP-532140
DDB1 and CUL4 associated factor 11
IDBP-535010
DDB1 and CUL4 associated factor 11
IDBP-542016
DDB1 and CUL4 associated factor 11
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000100897:
This gene encodes a WD repeat-containing protein that interacts with the COP9 signalosome, a macromolecular complex that interacts with cullin-RING E3 ligases and regulates their activity by hydrolyzing cullin-Nedd8 conjugates. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:55560006-55570065
Strand Forward strand
Band C3
Transcripts
ENSMUST00000072530 ENSMUSP00000072344
ENSMUST00000117236 ENSMUSP00000113014
ENSMUST00000121622 ENSMUSP00000113202
ENSMUST00000117701 ENSMUSP00000113620
ENSMUST00000147981 ENSMUSP00000123453
ENSMUST00000151245
ENSMUST00000133256 ENSMUSP00000118404
ENSMUST00000150019 ENSMUSP00000117617
ENSMUST00000129310
ENSMUST00000127991
ENSMUST00000143431 ENSMUSP00000118762
ENSMUST00000150481 ENSMUSP00000119001
ENSMUST00000152681 ENSMUSP00000120296
ENSMUST00000128490 ENSMUSP00000114211
ENSMUST00000153638
ENSMUST00000143375 ENSMUSP00000121570
ENSMUST00000155029
ENSMUST00000145983
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
GO:0016567 protein ubiquitination
Cellular Component
GO:0080008 Cul4-RING E3 ubiquitin ligase complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000100897
View Gene Order
ENSBTAG00000021392
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.11535 Mm.488383
RefSeq NM_001199009 NM_133734 XM_006519081 XM_006519082 XM_006519083 XM_006519084 XM_006519085 XM_006519086 XM_006519087 XM_006519088 XM_006519089 XM_006519090 XM_006519091
OMIM
CCDS CCDS27115
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca