Version 5.4
Mus musculus Gene: Alg9
Summary
InnateDB Gene IDBG-164262.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Alg9
Gene Name asparagine-linked glycosylation 9 (alpha 1,2 mannosyltransferase)
Synonyms 8230402H15Rik; AI747665; B430313H07Rik; Dibd1
Species Mus musculus
Ensembl Gene ENSMUSG00000032059
Encoded Proteins
IDBP-164264
asparagine-linked glycosylation 9 homolog (yeast, alpha 1,2 mannosyltransferase)
IDBP-533816
asparagine-linked glycosylation 9 homolog (yeast, alpha 1,2 mannosyltransferase)
IDBP-538080
asparagine-linked glycosylation 9 homolog (yeast, alpha 1,2 mannosyltransferase)
IDBP-741741
IDBP-741925
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000086848:
This gene encodes an alpha-1,2-mannosyltransferase enzyme that functions in lipid-linked oligosaccharide assembly. Mutations in this gene result in congenital disorder of glycosylation type Il. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:50775019-50843542
Strand Forward strand
Band A5.3
Transcripts
ENSMUST00000034561 ENSMUSP00000034561
ENSMUST00000162073 ENSMUSP00000125425
ENSMUST00000159576 ENSMUSP00000123711
ENSMUST00000162363
ENSMUST00000162442
ENSMUST00000161200
ENSMUST00000162596
ENSMUST00000175728 ENSMUSP00000135023
ENSMUST00000177320 ENSMUSP00000134818
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0016757 transferase activity, transferring glycosyl groups
GO:0052918 dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity
GO:0052926 dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity
Biological Process
GO:0006486 protein glycosylation
GO:0008152 metabolic process
GO:0097502 mannosylation
Cellular Component
GO:0005575 cellular_component
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000086848
View Gene Order
ENSBTAG00000020279
Not yet available
Pathways
NETPATH
REACTOME
REACT_262413
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
REACT_247926
Metabolism of proteins pathway
REACT_236283
Post-translational protein modification pathway
REACT_237472
Asparagine N-linked glycosylation pathway
KEGG
mmu00510
N-Glycan biosynthesis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_22433
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
REACT_22426
Asparagine N-linked glycosylation pathway
REACT_22161
Post-translational protein modification pathway
REACT_17015
Metabolism of proteins pathway
KEGG
hsa00510
N-Glycan biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.160035
RefSeq NM_133981 XM_006509903
OMIM
CCDS CCDS23175
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca