Version 5.4
Mus musculus Gene: Pknox1
Summary
InnateDB Gene IDBG-164528.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pknox1
Gene Name Pbx/knotted 1 homeobox
Synonyms D17Wsu76e; PREP1
Species Mus musculus
Ensembl Gene ENSMUSG00000006705
Encoded Proteins
IDBP-164530
Pbx/knotted 1 homeobox
IDBP-713072
IDBP-715533
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000160199:
Gene Information
Type Protein coding
Genomic Location Chromosome 17:31564749-31607684
Strand Forward strand
Band B1
Transcripts
ENSMUST00000097352 ENSMUSP00000094966
ENSMUST00000175709
ENSMUST00000175812
ENSMUST00000176895
ENSMUST00000176513
ENSMUST00000175806 ENSMUSP00000134852
ENSMUST00000176701 ENSMUSP00000135804
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated
Total 12 [view]
Protein-Protein 11 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003705 RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0001525 angiogenesis
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
GO:0030097 hemopoiesis
GO:0030217 T cell differentiation
GO:0030218 erythrocyte differentiation
GO:0043010 camera-type eye development
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription factor complex
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000160199
View Gene Order
ENSBTAG00000014153
Not yet available
Cross-References
SwissProt O70477
TrEMBL
UniProt Splice Variant
Entrez Gene 18771
UniGene Mm.259295 Mm.401586
RefSeq NM_016670 XM_006523857 XM_006523854 XM_006523855 XM_006523856 XM_006523858
OMIM
CCDS CCDS28608
HPRD
IMGT
MGI ID MGI:1201409
MGI Symbol Pknox1
EMBL AF061270 AK131788 AK134000 BC052701
GenPept AAC15990 AAH52701 BAE20805 BAE21975
RNA Seq Atlas 18771

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca