Version 5.4
Mus musculus Gene: Pcyox1
Summary
InnateDB Gene IDBG-164587.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pcyox1
Gene Name prenylcysteine oxidase 1
Synonyms 1200015P13Rik; AI115532; AI448340; PCL1; Pcly
Species Mus musculus
Ensembl Gene ENSMUSG00000029998
Encoded Proteins
IDBP-164589
prenylcysteine oxidase 1
IDBP-532845
prenylcysteine oxidase 1
IDBP-539591
prenylcysteine oxidase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000116005:
Prenylcysteine is released during the degradation of prenylated proteins. PCYOX1 catalyzes the degradation of prenylcysteine to yield free cysteines and a hydrophobic isoprenoid product (Tschantz et al., 1999 [PubMed 10585463]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:86386006-86397150
Strand Reverse strand
Band D1
Transcripts
ENSMUST00000032065 ENSMUSP00000032065
ENSMUST00000131500 ENSMUSP00000122602
ENSMUST00000153723 ENSMUSP00000119449
ENSMUST00000129650
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 14 [view]
Protein-Protein 14 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001735 prenylcysteine oxidase activity
GO:0008555 chloride-transporting ATPase activity
GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor
Biological Process
GO:0006821 chloride transport
GO:0030327 prenylated protein catabolic process
GO:0030328 prenylcysteine catabolic process
GO:0055114 oxidation-reduction process
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0005764 lysosome
GO:0005886 plasma membrane
GO:0034361 very-low-density lipoprotein particle
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000116005
View Gene Order
ENSBTAG00000002783
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu00900
Terpenoid backbone biosynthesis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00900
Terpenoid backbone biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 66881
UniGene Mm.30849 Mm.398024 Mm.399252 Mm.407277
RefSeq NM_025823 XM_006506486
OMIM
CCDS CCDS20311
HPRD
IMGT
MGI ID MGI:1914131
MGI Symbol Pcyox1
EMBL
GenPept
RNA Seq Atlas 66881

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca