Version 5.4
Mus musculus Gene: Xpnpep3
Summary
InnateDB Gene IDBG-164719.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Xpnpep3
Gene Name X-prolyl aminopeptidase (aminopeptidase P) 3, putative
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000022401
Encoded Proteins
IDBP-164721
X-prolyl aminopeptidase (aminopeptidase P) 3, putative
IDBP-621909
X-prolyl aminopeptidase (aminopeptidase P) 3, putative
IDBP-621916
X-prolyl aminopeptidase (aminopeptidase P) 3, putative
IDBP-621917
X-prolyl aminopeptidase (aminopeptidase P) 3, putative
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000196236:
The protein encoded by this gene belongs to the family of X-pro-aminopeptidases that utilize a metal cofactor, and remove the N-terminal amino acid from peptides with a proline residue in the penultimate position. This protein has been shown to localize to the mitochondria of renal cells, and have a role in ciliary function. Mutations in this gene are associated with nephronophthisis-like nephropathy-1. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene, however, expression of some of these isoforms in vivo is not known.[provided by RefSeq, Mar 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:81400138-81456807
Strand Forward strand
Band E1
Transcripts
ENSMUST00000041609 ENSMUSP00000038331
ENSMUST00000163754 ENSMUSP00000132822
ENSMUST00000163296
ENSMUST00000166831
ENSMUST00000165258 ENSMUSP00000130255
ENSMUST00000167799 ENSMUSP00000126038
ENSMUST00000164144
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004177 aminopeptidase activity
GO:0030145 manganese ion binding
Biological Process
GO:0003094 glomerular filtration
GO:0006508 proteolysis
GO:0016485 protein processing
Cellular Component
GO:0005739 mitochondrion
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000196236
View Gene Order
ENSBTAG00000006204
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.296441 Mm.390833 Mm.410525
RefSeq NM_177310 XM_006521086 XM_006521087
OMIM
CCDS CCDS27668
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca