InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Col6a2

Summary

InnateDB Gene

IDBG-165968.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Col6a2

Gene Name

collagen, type VI, alpha 2

Synonyms

Col6a-2

Species

Mus musculus

Ensembl Gene

ENSMUSG00000020241

Encoded Proteins

IDBP-165970

collagen, type VI, alpha 2

IDBP-270930

collagen, type VI, alpha 2

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000142173:
This gene encodes one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues. The product of this gene contains several domains similar to von Willebrand Factor type A domains. These domains have been shown to bind extracellular matrix proteins, an interaction that explains the importance of this collagen in organizing matrix components. Mutations in this gene are associated with Bethlem myopathy and Ullrich scleroatonic muscular dystrophy. Three transcript variants have been identified for this gene. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 10:76595762-76623630

Strand

Reverse strand

Band

Transcripts

ENSMUST00000001181	ENSMUSP00000001181
ENSMUST00000105413	ENSMUSP00000101053
ENSMUST00000137365

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0007155	cell adhesion
GO:0009749	response to glucose
GO:0070208	protein heterotrimerization

Cellular Component

GO:0005576	extracellular region
GO:0005578	proteinaceous extracellular matrix
GO:0005581	collagen trimer
GO:0005615	extracellular space
GO:0031012	extracellular matrix
GO:0042383	sarcolemma
GO:0043234	protein complex
GO:0070062	extracellular vesicular exosome