Version 5.4
Mus musculus Gene: Slit1
Summary
InnateDB Gene IDBG-166017.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slit1
Gene Name slit homolog 1 (Drosophila)
Synonyms mKIAA0813; Slil1
Species Mus musculus
Ensembl Gene ENSMUSG00000025020
Encoded Proteins
IDBP-166019
slit homolog 1 (Drosophila)
IDBP-621512
slit homolog 1 (Drosophila)
IDBP-621514
slit homolog 1 (Drosophila)
IDBP-621515
slit homolog 1 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000187122:
Gene Information
Type Protein coding
Genomic Location Chromosome 19:41600257-41743665
Strand Reverse strand
Band C3
Transcripts
ENSMUST00000025993 ENSMUSP00000025993
ENSMUST00000169141 ENSMUSP00000129034
ENSMUST00000166496 ENSMUSP00000128381
ENSMUST00000169416
ENSMUST00000171586 ENSMUSP00000126139
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0043395 heparan sulfate proteoglycan binding
GO:0048495 Roundabout binding
Biological Process
GO:0007409 axonogenesis
GO:0007411 axon guidance
GO:0007420 brain development
GO:0008045 motor neuron axon guidance
GO:0021510 spinal cord development
GO:0021772 olfactory bulb development
GO:0022028 tangential migration from the subventricular zone to the olfactory bulb
GO:0022029 telencephalon cell migration
GO:0031290 retinal ganglion cell axon guidance
GO:0033563 dorsal/ventral axon guidance
GO:0040023 establishment of nucleus localization
GO:0048812 neuron projection morphogenesis
GO:0048843 negative regulation of axon extension involved in axon guidance
GO:0048846 axon extension involved in axon guidance
GO:0050919 negative chemotaxis
GO:0051964 negative regulation of synapse assembly
Cellular Component
GO:0005615 extracellular space
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000187122
View Gene Order
ENSBTAG00000043991
Not yet available
Pathways
NETPATH
REACTOME
REACT_229826
Netrin-1 signaling pathway
REACT_261444
Axon guidance pathway
REACT_188576
Developmental Biology pathway
KEGG
mmu04360
Axon guidance pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_22237
Netrin-1 signaling pathway
REACT_111045
Developmental Biology pathway
REACT_18266
Axon guidance pathway
KEGG
hsa04360
Axon guidance pathway
INOH
PID NCI
ajdiss_2pathway
Posttranslational regulation of adherens junction stability and dissassembly
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.40322
RefSeq NM_015748
OMIM
CCDS CCDS29812
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca