InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Creb3l4

Summary

InnateDB Gene

IDBG-166231.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Creb3l4

Gene Name

cAMP responsive element binding protein 3-like 4

Synonyms

1700012K17Rik; 5330432F22Rik; AIBZIP; Atce1; AV040530; AV258827; CREB3; CREB4; JAL; mJAL; TISP40; Tisp40alpha; Tisp40beta

Species

Mus musculus

Ensembl Gene

ENSMUSG00000027938

Encoded Proteins

IDBP-166233

cAMP responsive element binding protein 3-like 4

IDBP-266814

cAMP responsive element binding protein 3-like 4

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143578:
This gene encodes a CREB (cAMP responsive element binding) protein with a transmembrane domain which localizes it to the ER membrane. The encoded protein is a transcriptional activator which contains a dimerization domain, and this protein may function in a number of processing pathways including protein processing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 3:90237500-90243512

Strand

Reverse strand

Band

Transcripts

ENSMUST00000029547	ENSMUSP00000029547
ENSMUST00000107369	ENSMUSP00000102992

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.

Experimentally validated
Total	11 [view]
Protein-Protein	11 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	11 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001228	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0006986	response to unfolded protein
GO:0007275	multicellular organismal development
GO:0007283	spermatogenesis
GO:0030154	cell differentiation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter

Cellular Component

GO:0002079	inner acrosomal membrane
GO:0005634	nucleus
GO:0005783	endoplasmic reticulum
GO:0005789	endoplasmic reticulum membrane
GO:0016021	integral component of membrane

Orthologs

Species

Homo sapiens

Bos taurus

Gene ID

Gene Order

ENSG00000143578

View Gene Order

ENSBTAG00000014692

Not yet available

Pathways

NETPATH

REACTOME

KEGG

mmu04916

Melanogenesis pathway

mmu05215

Prostate cancer pathway

mmu05016

Huntington's disease pathway

mmu04962

Vasopressin-regulated water reabsorption pathway

INOH

PID NCI

Pathway Predictions based on Human Orthology Data

NETPATH

REACTOME

KEGG

hsa05215

Prostate cancer pathway

hsa04916

Melanogenesis pathway

hsa05016

Huntington's disease pathway

hsa04962

Vasopressin-regulated water reabsorption pathway

INOH

PID NCI

Cross-References

SwissProt

Q9D2A5

TrEMBL

UniProt Splice Variant

Entrez Gene

78284

UniGene

Mm.299952

RefSeq

NM_030080 XM_006502310 XM_006502311 XM_006502312 XM_006502313

OMIM

CCDS

CCDS17524

HPRD

IMGT

MGI ID

MGI:1916603

MGI Symbol

Creb3l4

EMBL

AB047647 AB052779 AB182651 AB182652 AF287260 AK005918 AK019928 AK088919 AY049978 BC022605

GenPept

AAH22605 AAK73568 AAL13158 BAB24315 BAB31922 BAB97209 BAC40653 BAC45036 BAD26707 BAD26708

RNA Seq Atlas

78284