Version 5.4
| Mus musculus Gene: Slc19a1 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-166498.7 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Slc19a1 | ||||||||
| Gene Name | solute carrier family 19 (folate transporter), member 1 | ||||||||
| Synonyms | AI323572; RFC; RFC-1; RFC1 | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000001436 | ||||||||
| Encoded Proteins |
solute carrier family 19 (sodium/hydrogen exchanger), member 1
solute carrier family 19 (sodium/hydrogen exchanger), member 1
solute carrier family 19 (sodium/hydrogen exchanger), member 1
solute carrier family 19 (sodium/hydrogen exchanger), member 1
solute carrier family 19 (sodium/hydrogen exchanger), member 1
solute carrier family 19 (sodium/hydrogen exchanger), member 1
solute carrier family 19 (sodium/hydrogen exchanger), member 1
solute carrier family 19 (sodium/hydrogen exchanger), member 1
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000173638:
The membrane protein encoded by this gene is a transporter of folate and is involved in the regulation of intracellular concentrations of folate. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 10:77032241-77061002 | ||||||||
| Strand | Forward strand | ||||||||
| Band | C1 | ||||||||
| Transcripts | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME |
Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF pathway
Disease pathway
Metabolism pathway
Defective AMN causes hereditary megaloblastic anemia 1 pathway
Defective GIF causes intrinsic factor deficiency pathway
Defective MMAA causes methylmalonic aciduria type cblA pathway
Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC pathway
Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD pathway
Defective CD320 causes methylmalonic aciduria pathway
Defective MUT causes methylmalonic aciduria mut type pathway
Defects in biotin (Btn) metabolism pathway
Defective BTD causes biotidinase deficiency pathway
Defective MMAB causes methylmalonic aciduria type cblB pathway
Defective MTR causes methylmalonic aciduria and homocystinuria type cblG pathway
Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE pathway
Defective CUBN causes hereditary megaloblastic anemia 1 pathway
Metabolism of vitamins and cofactors pathway
Metabolism of folate and pterines pathway
Metabolism of water-soluble vitamins and cofactors pathway
Defects in vitamin and cofactor metabolism pathway
Defects in cobalamin (B12) metabolism pathway
Defective TCN2 causes hereditary megaloblastic anemia pathway
Defective HLCS causes multiple carboxylase deficiency pathway
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| KEGG | |||||||||
| INOH | |||||||||
| PID NCI | |||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
Metabolism of folate and pterines pathway
Defective HLCS causes multiple carboxylase deficiency pathway
Defective MUT causes methylmalonic aciduria mut type pathway
Defective MMAA causes methylmalonic aciduria type cblA pathway
Defective TCN2 causes hereditary megaloblastic anemia pathway
Metabolism of water-soluble vitamins and cofactors pathway
Defective AMN causes hereditary megaloblastic anemia 1 pathway
Defective MTR causes methylmalonic aciduria and homocystinuria type cblG pathway
Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF pathway
Defective CD320 causes methylmalonic aciduria pathway
Defects in cobalamin (B12) metabolism pathway
Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC pathway
Defects in biotin (Btn) metabolism pathway
Defective BTD causes biotidinase deficiency pathway
Defective GIF causes intrinsic factor deficiency pathway
Defects in vitamin and cofactor metabolism pathway
Defective CUBN causes hereditary megaloblastic anemia 1 pathway
Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD pathway
Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE pathway
Metabolism pathway
Defective MMAB causes methylmalonic aciduria type cblB pathway
Disease pathway
Metabolism of vitamins and cofactors pathway
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| KEGG | |||||||||
| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | P41438 | ||||||||
| TrEMBL | D3YU74 D3YZE1 D3Z0I6 D3Z4F3 E9Q8X6 Q542F3 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 20509 | ||||||||
| UniGene | Mm.265060 Mm.486579 | ||||||||
| RefSeq | NM_001199271 NM_031196 XM_006513414 XM_006513415 XM_006513416 XM_006513417 XM_006513418 XM_006513420 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS35947 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | MGI:103182 | ||||||||
| MGI Symbol | Slc19a1 | ||||||||
| EMBL | AC055777 AK079592 AK088803 BC015263 CH466553 L23755 L36539 U32469 U57781 U57782 U57783 U57784 U57785 U66103 | ||||||||
| GenPept | AAA39738 AAB38483 AAC52258 AAC53287 AAC53288 AAC53289 AAC53290 AAC53291 AAH15263 BAC37693 BAC40582 EDL31821 EDL31822 EDL31823 EDL31824 | ||||||||
| RNA Seq Atlas | 20509 | ||||||||