Version 5.4
Mus musculus Gene: Brwd3
Summary
InnateDB Gene IDBG-167844.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Brwd3
Gene Name bromodomain and WD repeat domain containing 3
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000063663
Encoded Proteins
IDBP-622464
bromodomain and WD repeat domain containing 3
IDBP-167850
bromodomain and WD repeat domain containing 3
IDBP-539972
bromodomain and WD repeat domain containing 3
IDBP-622465
bromodomain and WD repeat domain containing 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000165288:
The protein encoded by this gene contains a bromodomain and several WD repeats. It is thought to have a chromatin-modifying function, and may thus play a role in transcription. Mutations in this gene cause mental retardation X-linked type 93, which is also referred to as mental retardation X-linked with macrocephaly. This gene is also associated with translocations in patients with B-cell chronic lymphocytic leukemia. [provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome X:108737016-108834372
Strand Reverse strand
Band D
Transcripts
ENSMUST00000041866 ENSMUSP00000134621
ENSMUST00000101283 ENSMUSP00000098841
ENSMUST00000150434 ENSMUSP00000123588
ENSMUST00000144521 ENSMUSP00000133674
ENSMUST00000134434
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0007010 cytoskeleton organization
GO:0008360 regulation of cell shape
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000165288
View Gene Order
ENSBTAG00000016230
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.100112 Mm.404226 Mm.404234 Mm.413432 Mm.426127
RefSeq NM_001081477
OMIM
CCDS CCDS41100
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca