Version 5.4
Homo sapiens Gene: COBL
Summary
InnateDB Gene IDBG-16785.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol COBL
Gene Name cordon-bleu homolog (mouse)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000106078
Encoded Proteins
IDBP-16787
cordon-bleu homolog (mouse)
IDBP-239338
cordon-bleu homolog (mouse)
IDBP-239340
cordon-bleu homolog (mouse)
IDBP-375492
cordon-bleu homolog (mouse)
IDBP-375494
cordon-bleu homolog (mouse)
IDBP-375503
cordon-bleu homolog (mouse)
IDBP-375505
cordon-bleu homolog (mouse)
IDBP-375508
cordon-bleu homolog (mouse)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 7:51016212-51316818
Strand Reverse strand
Band p12.1
Transcripts
ENST00000265136 ENSP00000265136
ENST00000395542 ENSP00000378912
ENST00000395540 ENSP00000378910
ENST00000445054 ENSP00000401204
ENST00000431948 ENSP00000413498
ENST00000452534 ENSP00000405059
ENST00000441453 ENSP00000399500
ENST00000449281 ENSP00000391864
ENST00000462395
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0003785 actin monomer binding
GO:0005515 protein binding
Biological Process
GO:0000578 embryonic axis specification
GO:0001757 somite specification
GO:0001843 neural tube closure
GO:0001889 liver development
GO:0030041 actin filament polymerization
GO:0030903 notochord development
GO:0033504 floor plate development
GO:0048565 digestive tract development
GO:0048669 collateral sprouting in absence of injury
GO:0051639 actin filament network formation
GO:1900006 positive regulation of dendrite development
Cellular Component
GO:0001726 ruffle
GO:0005884 actin filament
GO:0005886 plasma membrane
GO:0005938 cell cortex
GO:0016020 membrane
GO:0030424 axon
GO:0030425 dendrite
GO:0043025 neuronal cell body
GO:0044294 dendritic growth cone
GO:0044295 axonal growth cone
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000020173
View Gene Order
ENSBTAG00000023806
Not yet available
Cross-References
SwissProt
TrEMBL H7C1N2
UniProt Splice Variant
Entrez Gene 23242
UniGene Hs.597295 Hs.666338 Hs.669626 Hs.99141
RefSeq XM_005271756 XM_006715675 NM_001287436 NM_001287438 NM_015198 XM_005271750 XM_005271751 XM_005271757
HUGO HGNC:22199
OMIM 610317
CCDS CCDS34637 CCDS75601 CCDS75602
HPRD 10843
IMGT
EMBL AC004414 AC005535 AC012372
GenPept
RNA Seq Atlas 23242

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca