Version 5.4
Mus musculus Gene: Mcat
Summary
InnateDB Gene IDBG-168346.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mcat
Gene Name malonyl CoA:ACP acyltransferase (mitochondrial)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000048755
Encoded Proteins
IDBP-168348
malonyl CoA:ACP acyltransferase (mitochondrial)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000100294:
The protein encoded by this gene is found exclusively in the mitochondrion, where it catalyzes the transfer of a malonyl group from malonyl-CoA to the mitochondrial acyl carrier protein. The encoded protein may be part of a fatty acid synthase complex that is more like the type II prokaryotic and plastid complexes rather than the type I human cytosolic complex. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:83546797-83555711
Strand Reverse strand
Band E1
Transcripts
ENSMUST00000061882 ENSMUSP00000051569
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004314 [acyl-carrier-protein] S-malonyltransferase activity
GO:0016740 transferase activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006633 fatty acid biosynthetic process
GO:0008152 metabolic process
Cellular Component
GO:0005739 mitochondrion
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000100294
View Gene Order
ENSBTAG00000002413
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu00061
Fatty acid biosynthesis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00061
Fatty acid biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt Q8R3F5
TrEMBL
UniProt Splice Variant
Entrez Gene 223722
UniGene Mm.37560
RefSeq NM_001030014 XM_006520814
OMIM
CCDS CCDS27704
HPRD
IMGT
MGI ID MGI:2388651
MGI Symbol Mcat
EMBL BC025519 BC099494
GenPept AAH25519 AAH99494
RNA Seq Atlas 223722

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca