Version 5.4
Mus musculus Gene: Klhl4
Summary
InnateDB Gene IDBG-169054.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Klhl4
Gene Name kelch-like 4 (Drosophila)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000025597
Encoded Proteins
IDBP-169056
kelch-like 4 (Drosophila)
IDBP-254017
kelch-like 4 (Drosophila)
IDBP-254019
kelch-like 4 (Drosophila)
IDBP-542122
kelch-like 4 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000102271:
This gene encodes a member of the kelch family of proteins, which are characterized by kelch repeat motifs and a POZ/BTB protein-binding domain. It is thought that kelch repeats are actin binding domains. However, the specific function of this protein has not been determined. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome X:114474333-114560829
Strand Forward strand
Band E1
Transcripts
ENSMUST00000040504 ENSMUSP00000038080
ENSMUST00000113371 ENSMUSP00000108998
ENSMUST00000113370 ENSMUSP00000108997
ENSMUST00000133447 ENSMUSP00000118072
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0005730 nucleolus
GO:0015630 microtubule cytoskeleton
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000102271
View Gene Order
ENSBTAG00000005219
Not yet available
Cross-References
SwissProt
TrEMBL Q811G7 Q8BUX1
UniProt Splice Variant
Entrez Gene 237010
UniGene Mm.132583
RefSeq NM_172781 NM_001290477 NM_001290478 XM_006528385
OMIM
CCDS CCDS41108 CCDS72423
HPRD
IMGT
MGI ID MGI:2442829
MGI Symbol Klhl4
EMBL AK081937 BC046395 BX005189
GenPept AAH46395 BAC38376
RNA Seq Atlas 237010

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca