Version 5.4
Mus musculus Gene: Arhgap10
Summary
InnateDB Gene IDBG-169225.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Arhgap10
Gene Name Rho GTPase activating protein 10
Synonyms A930033B01Rik; PSGAP-m; PSGAP-s
Species Mus musculus
Ensembl Gene ENSMUSG00000037148
Encoded Proteins
IDBP-169227
Rho GTPase activating protein 10
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000071205:
Gene Information
Type Protein coding
Genomic Location Chromosome 8:77250366-77517907
Strand Reverse strand
Band C1
Transcripts
ENSMUST00000076316 ENSMUSP00000075658
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005100 Rho GTPase activator activity
GO:0005515 protein binding
Biological Process
GO:0007010 cytoskeleton organization
GO:0007165 signal transduction
GO:0032321 positive regulation of Rho GTPase activity
GO:0043066 negative regulation of apoptotic process
Cellular Component
GO:0005622 intracellular
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000071205
View Gene Order
ENSBTAG00000002531
Not yet available
Pathways
NETPATH
REACTOME
REACT_258521
Apoptosis pathway
REACT_206918
Signaling by Rho GTPases pathway
REACT_227606
Regulation of Apoptosis pathway
REACT_223446
Regulation of PAK-2p34 activity by PS-GAP/RHG10 pathway
REACT_210090
Rho GTPase cycle pathway
REACT_188257
Signal Transduction pathway
KEGG
mmu05100
Bacterial invasion of epithelial cells pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_11051
Rho GTPase cycle pathway
REACT_13528
Regulation of PAK-2p34 activity by PS-GAP/RHG10 pathway
REACT_11044
Signaling by Rho GTPases pathway
REACT_578
Apoptosis pathway
REACT_111102
Signal Transduction pathway
REACT_13648
Regulation of Apoptosis pathway
REACT_223911
Regulation of Apoptosis pathway
REACT_211150
Rho GTPase cycle pathway
REACT_214353
Signal Transduction pathway
REACT_209608
Signaling by Rho GTPases pathway
REACT_214193
Regulation of PAK-2p34 activity by PS-GAP/RHG10 pathway
REACT_219454
Apoptosis pathway
KEGG
hsa05100
Bacterial invasion of epithelial cells pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.165974
RefSeq NM_030113 XM_006531494 XM_006531499 XM_006531500 XM_006531501
OMIM
CCDS CCDS22425
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca