Version 5.4
Mus musculus Gene: Rcbtb1
Summary
InnateDB Gene IDBG-169566.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rcbtb1
Gene Name regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
Synonyms 5430409I18Rik; AW111883; CLLD7; CLLL7
Species Mus musculus
Ensembl Gene ENSMUSG00000035469
Encoded Proteins
IDBP-169568
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
IDBP-169570
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
IDBP-620346
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
IDBP-620347
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
IDBP-620342
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
IDBP-620345
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
IDBP-620348
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
IDBP-620349
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000136144:
This gene encodes a protein with an N-terminal RCC1 domain and a C-terminal BTB (broad complex, tramtrack and bric-a-brac) domain. In rat, over-expression of this gene in vascular smooth muscle cells induced cellular hypertrophy. In rat, the C-terminus of RCBTB1 interacts with the angiotensin II receptor-1A. In humans, this gene maps to a region of chromosome 13q that is frequently deleted in B-cell chronic lymphocytic leukemia and other lymphoid malignancies. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:59201209-59237265
Strand Forward strand
Band C3
Transcripts
ENSMUST00000043227 ENSMUSP00000037030
ENSMUST00000022551 ENSMUSP00000022551
ENSMUST00000095778
ENSMUST00000140136 ENSMUSP00000134515
ENSMUST00000142326 ENSMUSP00000134542
ENSMUST00000153225
ENSMUST00000147280
ENSMUST00000173547 ENSMUSP00000134360
ENSMUST00000174009 ENSMUSP00000133369
ENSMUST00000172810 ENSMUSP00000134284
ENSMUST00000174830 ENSMUSP00000133421
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007049 cell cycle
GO:0016568 chromatin modification
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000136144
View Gene Order
ENSBTAG00000034269
Not yet available
Cross-References
SwissProt Q6NXM2
TrEMBL G3UZ62 G3UZL2 Q8BTL0
UniProt Splice Variant
Entrez Gene 71330
UniGene Mm.234195 Mm.407786
RefSeq XM_006519566 XM_006519568 XM_006519569 NM_027764 XM_006519567
OMIM
CCDS CCDS27168
HPRD
IMGT
MGI ID MGI:1918580
MGI Symbol Rcbtb1
EMBL AC166169 AK033501 AK088299 AK089923 BC067005
GenPept AAH67005 BAC28324 BAC40268 BAC40997
RNA Seq Atlas 71330

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca