Version 5.4
Homo sapiens Gene: OR1E2
Summary
InnateDB Gene IDBG-16985.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol OR1E2
Gene Name olfactory receptor, family 1, subfamily E, member 2
Synonyms OR17-135; OR17-93; OR1E4; OR1E7; OST529
Species Homo sapiens
Ensembl Gene ENSG00000127780
Encoded Proteins
IDBP-16987
olfactory receptor, family 1, subfamily E, member 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:3432870-3433841
Strand Reverse strand
Band p13.2
Transcripts
ENST00000248384 ENSP00000248384
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0004930 G-protein coupled receptor activity
GO:0004984 olfactory receptor activity
Biological Process
GO:0007165 signal transduction
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007606 sensory perception of chemical stimulus
GO:0050911 detection of chemical stimulus involved in sensory perception of smell
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_15488
Olfactory Signaling Pathway pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
KEGG
hsa04740
Olfactory transduction pathway
INOH
PID NCI
Cross-References
SwissProt P47887
TrEMBL Q6IFM7
UniProt Splice Variant
Entrez Gene 8388
UniGene Hs.533931
RefSeq NM_003554
HUGO HGNC:8190
OMIM
CCDS CCDS11026
HPRD
IMGT
EMBL AF087925 AF095725 AF399551 BC121105 BC121106 BK004235 U04686 U76377 U86241 U86242
GenPept AAA18349 AAC39621 AAC39622 AAD00249 AAF03260 AAF37315 AAI21106 AAI21107 AAK95036 DAA04633
RNA Seq Atlas 8388

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca