Version 5.4
Mus musculus Gene: Epha6
Summary
InnateDB Gene IDBG-170096.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Epha6
Gene Name Eph receptor A6
Synonyms Ehk2; Hek12; m-ehk2
Species Mus musculus
Ensembl Gene ENSMUSG00000055540
Encoded Proteins
IDBP-170098
Eph receptor A6
IDBP-542848
Eph receptor A6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000080224:
Gene Information
Type Protein coding
Genomic Location Chromosome 16:59653483-60605531
Strand Reverse strand
Band C1.3
Transcripts
ENSMUST00000068860 ENSMUSP00000066734
ENSMUST00000161358 ENSMUSP00000124340
ENSMUST00000159383
ENSMUST00000162129
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005003 ephrin receptor activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006468 protein phosphorylation
GO:0018108 peptidyl-tyrosine phosphorylation
GO:0048013 ephrin receptor signaling pathway
Cellular Component
GO:0005634 nucleus
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000080224
View Gene Order
ENSBTAG00000044111
Not yet available
Pathways
NETPATH
REACTOME
REACT_243939
EPHA-mediated growth cone collapse pathway
REACT_243590
EPH-ephrin mediated repulsion of cells pathway
REACT_258158
EPH-Ephrin signaling pathway
REACT_261444
Axon guidance pathway
REACT_188576
Developmental Biology pathway
KEGG
mmu04360
Axon guidance pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_111045
Developmental Biology pathway
REACT_18266
Axon guidance pathway
REACT_228063
EPHA-mediated growth cone collapse pathway
REACT_228189
EPH-ephrin mediated repulsion of cells pathway
REACT_228170
EPH-Ephrin signaling pathway
KEGG
hsa04360
Axon guidance pathway
INOH
PID NCI
Cross-References
SwissProt Q62413
TrEMBL G1K381
UniProt Splice Variant
Entrez Gene 13840
UniGene Mm.455790
RefSeq NM_007938
OMIM
CCDS CCDS28260
HPRD
IMGT
MGI ID MGI:108034
MGI Symbol Epha6
EMBL AC118603 AC122318 AC131707 AC133940 AC134526 AC154212 AC154473 AC154632 AK032436 BC141090 CH466521 CT009682 U58332
GenPept AAB53836 AAI41091 BAC27868 EDK98232
RNA Seq Atlas 13840

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca