Version 5.4
Mus musculus Gene: Tmem165
Summary
InnateDB Gene IDBG-172796.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tmem165
Gene Name transmembrane protein 165
Synonyms AV026557; pFT27; Tpardl; Tparl
Species Mus musculus
Ensembl Gene ENSMUSG00000029234
Encoded Proteins
IDBP-172798
transmembrane protein 165
IDBP-532143
transmembrane protein 165
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000134851:
This gene encodes a predicted transmembrane protein with a perinuclear Golgi-like distribution in fibroblasts. Mutations in this gene are associated with the autosomal recessive disorder congenital disorder of glycosylation, type IIk. Knockdown of this gene's expression causes decreased sialylation in HEK cells and suggests this gene plays a role in terminal Golgi glycosylation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:76183880-76209245
Strand Forward strand
Band C3.3
Transcripts
ENSMUST00000031144 ENSMUSP00000031144
ENSMUST00000136424
ENSMUST00000130842 ENSMUSP00000114647
ENSMUST00000138544
ENSMUST00000153633
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0006487 protein N-linked glycosylation
GO:0006874 cellular calcium ion homeostasis
GO:0032472 Golgi calcium ion transport
GO:0035751 regulation of lysosomal lumen pH
Cellular Component
GO:0000139 Golgi membrane
GO:0005765 lysosomal membrane
GO:0005794 Golgi apparatus
GO:0010008 endosome membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031901 early endosome membrane
GO:0031902 late endosome membrane
GO:0032588 trans-Golgi network membrane
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000134851
View Gene Order
ENSBTAG00000001269
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.407097 Mm.790
RefSeq NM_011626
OMIM
CCDS CCDS19359
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca