Version 5.4
Mus musculus Gene: Exoc1
Summary
InnateDB Gene IDBG-173213.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Exoc1
Gene Name exocyst complex component 1
Synonyms 2810407P21Rik; A730011E05Rik; SEC3; Sec3l1; Sec3p
Species Mus musculus
Ensembl Gene ENSMUSG00000036435
Encoded Proteins
IDBP-173215
exocyst complex component 1
IDBP-173217
exocyst complex component 1
IDBP-253754
exocyst complex component 1
IDBP-538073
exocyst complex component 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000090989:
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:76529311-76570294
Strand Forward strand
Band C3.3
Transcripts
ENSMUST00000049469 ENSMUSP00000046719
ENSMUST00000087133 ENSMUSP00000084373
ENSMUST00000113493 ENSMUSP00000109121
ENSMUST00000150829
ENSMUST00000131470
ENSMUST00000137018
ENSMUST00000141884
ENSMUST00000132807
ENSMUST00000143489
ENSMUST00000134521 ENSMUSP00000121784
ENSMUST00000143736
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 32 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 32 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0006887 exocytosis
GO:0008150 biological_process
GO:0015031 protein transport
Cellular Component
GO:0005575 cellular_component
GO:0005886 plasma membrane
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000090989
View Gene Order
ENSBTAG00000032637
Not yet available
Pathways
NETPATH
REACTOME
REACT_209837
Membrane Trafficking pathway
REACT_247926
Metabolism of proteins pathway
REACT_206913
Peptide hormone metabolism pathway
REACT_207837
Insulin processing pathway
REACT_199054
Translocation of GLUT4 to the plasma membrane pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_15550
Insulin processing pathway
REACT_147867
Translocation of GLUT4 to the plasma membrane pathway
REACT_17015
Metabolism of proteins pathway
REACT_160078
Peptide hormone metabolism pathway
REACT_11123
Membrane Trafficking pathway
KEGG
INOH
PID NCI
arf6_traffickingpathway
Arf6 trafficking events
insulin_pathway
Insulin Pathway
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.403233 Mm.490678
RefSeq NM_001289770 NM_001289771 NM_027270 XM_006535211 XM_006535212 XM_006535213 XM_006535214
OMIM
CCDS CCDS39117 CCDS71607 CCDS71608
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca