Version 5.4
Mus musculus Gene: Arl3
Summary
InnateDB Gene IDBG-173310.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Arl3
Gene Name ADP-ribosylation factor-like 3
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000025035
Encoded Proteins
IDBP-173312
ADP-ribosylation factor-like 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000138175:
ADP-ribosylation factor-like 3 is a member of the ADP-ribosylation factor family of GTP-binding proteins. ARL3 binds guanine nucleotides but lacks ADP-ribosylation factor activity. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:46531109-46573085
Strand Reverse strand
Band C3
Transcripts
ENSMUST00000026009 ENSMUSP00000026009
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 8 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0004871 signal transducer activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0008017 microtubule binding
GO:0019001 guanyl nucleotide binding
GO:0019003 GDP binding
GO:0031683 G-protein beta/gamma-subunit complex binding
GO:0046872 metal ion binding
Biological Process
GO:0000910 cytokinesis
GO:0001822 kidney development
GO:0006184 GTP catabolic process
GO:0006886 intracellular protein transport
GO:0006892 post-Golgi vesicle-mediated transport
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007224 smoothened signaling pathway
GO:0007264 small GTPase mediated signal transduction
GO:0015031 protein transport
GO:0042073 intraciliary transport
GO:0042461 photoreceptor cell development
GO:0060271 cilium morphogenesis
Cellular Component
GO:0000139 Golgi membrane
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005813 centrosome
GO:0005876 spindle microtubule
GO:0005881 cytoplasmic microtubule
GO:0005886 plasma membrane
GO:0030496 midbody
GO:0032391 photoreceptor connecting cilium
GO:0070062 extracellular vesicular exosome
GO:0072372 primary cilium
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000138175
View Gene Order
ENSBTAG00000004318
Not yet available
Cross-References
SwissProt Q9WUL7
TrEMBL Q543P7
UniProt Splice Variant
Entrez Gene 56350
UniGene
RefSeq NM_019718
OMIM
CCDS CCDS38010
HPRD
IMGT
MGI ID MGI:1929699
MGI Symbol Arl3
EMBL AF143241 AK048644 BC042941
GenPept AAD33067 AAH42941 BAC33407
RNA Seq Atlas 56350

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca