Version 5.4
Homo sapiens Gene: CDHR5
Summary
InnateDB Gene IDBG-17352.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CDHR5
Gene Name cadherin-related family member 5
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000099834
Encoded Proteins
IDBP-17356
cadherin-related family member 5
IDBP-17358
cadherin-related family member 5
IDBP-235110
cadherin-related family member 5
IDBP-592294
cadherin-related family member 5
IDBP-594878
cadherin-related family member 5
IDBP-591859
cadherin-related family member 5
IDBP-594657
cadherin-related family member 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is a novel mucin-like gene that is a member of the cadherin superfamily. While encoding nonpolymorphic tandem repeats rich in proline, serine and threonine similar to mucin proteins, the gene also contains sequence encoding calcium-binding motifs found in all cadherins. The role of the hybrid extracellular region and the specific function of this protein have not yet been determined. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jan 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:616565-626078
Strand Reverse strand
Band p15.5
Transcripts
ENST00000358353 ENSP00000351118
ENST00000349570 ENSP00000345726
ENST00000397542 ENSP00000380676
ENST00000531177 ENSP00000437255
ENST00000531899
ENST00000532949
ENST00000526077 ENSP00000435082
ENST00000534311 ENSP00000436295
ENST00000531088 ENSP00000431505
ENST00000529337
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0008013 beta-catenin binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000025497
View Gene Order
ENSBTAG00000047914
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.165619
RefSeq NM_001171968 NM_021924 NM_031264
HUGO
OMIM
CCDS CCDS7707 CCDS7708
HPRD 06021
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca